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This medicine is used to deal with depression. Additionally it is used with other therapies for the treating nighttime bed-wetting (enuresis) in young ones. Using this medicine to treat depression might improve your mood, rest, appetite, and energy level and could help restore your desire for day-to-day living. Imipramine can help your child control nighttime bed-wetting.

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Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain substances that are naturalneurotransmitters like norepinephrine) in the brain. For bed-wetting, this medicine may work by blocking the impact of a particular substance that is naturalacetylcholine) on the bladder.

OTHER USES: This section contains uses of this drug which are not detailed in the approved professional labeling for the medication but that may be prescribed by your health care expert. Utilize this drug for an ailment that is listed in this section only if it has been so prescribed by your health care pro.

This drug may be used for also the treatment of panic and axiety problems.

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Read the drugs Guide available from your pharmacist. Consult your pharmacist or doctor if you have any questions.

Take this medication by lips with or without food, usually 1-4 times daily or as directed by the doctor. You to take the entire dose once daily at bedtime if you have daytime drowsiness, your doctor may direct. Dosage is based on your medical condition and response to therapy. In children, dosage may also be based on body weight. To reduce your risk of side effects, your doctor may start you at a low dose and gradually increase your dose.

When used in children for bed-wetting, imipramine must be taken one hour before bedtime. The drug may be given earlier in separate doses (e.g., one dose in the afternoon and one dose at bedtime) if your child usually wets the bed early in the night.

Follow your physician's instructions carefully. Do not take more or less medication or frequently take it more than prescribed. Your condition shall maybe not improve any faster and your threat of side effects will increase. Utilize this medicine regularly in order to obtain the benefit that is most from it. To help you remember, use it at the same time(s) each time.

This medication does not away work right. It may take up to 3 weeks before you experience the full benefits if you are taking this medication for depression.

It is crucial to continue taking this medication even though you feel great. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become even worse once the medication is abruptly stopped. Your dosage may gradually need to be reduced.

When used for a long period in kids for bed-wetting, this medication may not work as well and could require different dosing. Talk with the doctor if this medicine stops working well.

Inform your physician if your condition persists or worsens.

Negative Effects

Dry lips, blurred vision, headache, drowsiness, dizziness, constipation, nausea, vomiting, loss of appetite, diarrhea, stomach cramps, fat gain/loss, and increased sweating may occur. If any of these effects persist or worsen, notify your pharmacist or doctor quickly.

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Understand that your medical professional has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your physician immediately if some of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unusual breast milk production, irregular/painful menstrual periods, muscle stiffness, restlessness, tinnitus, sexual issues (e.g., decreased sexual ability, alterations in desire), shakiness (tremors), numbness/tingling of the hands/feet, pain/redness/swelling of hands or legs, trouble urinating.

Tell your doctor right away if any of the rare but really side that is serious occur: effortless bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medicine may increase serotonin and rarely cause a tremendously serious condition called serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

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Get help that is medical away when you yourself have any extremely serious side impacts, including: upper body discomfort, slow/fast/irregular heartbeat, fainting, seizures, slurred speech, weakness on one part associated with human anatomy, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights through the night).

An extremely serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This isn't a list that is complete of adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Call your medical professional for medical advice about side-effects. You may report side effects to FDA at 1-800-FDA-1088 or at

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In Canada - Call your doctor for medical advice about part results. You'll report adverse effects to Health Canada at 1-866-234-2345.


Before using this medication, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (such as desipramine, amitriptyline); or. This product may contain inactive ingredients, which could cause allergic reactions or other problems. Communicate with your pharmacist for lots more details.

This medication must not be used if you've got a particular medical condition. Before using this medicine, consult your doctor or pharmacist if you have had: a recent heart attack.

Before by using this medicine, inform your doctor or pharmacist your medical history, particularly of: difficulty in breathing (e.g., asthma, chronic bronchitis), individual or genealogy and family history of glaucoma (angle-closure type), diabetes, consuming disorders (e.g., bulimia), heart problems (e.g., arrhythmias, coronary artery disease), liver problems, kidney issues, personal or genealogy and family history of other mental/mood conditions (e.g., manic depression, schizophrenia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (age.g., due to enlarged prostate), any condition that may increase your risk of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive therapy, brain injury/disease such as for example stroke), certain kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Imipramine may cause a state of being which affects the center rhythm (QT prolongation). QT prolongation can hardly ever cause severe (rarely fatal) fast/irregular heartbeat as well as other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The possibility of QT prolongation may be increased when you have specific medical conditions or are taking other medications which could cause QT prolongation. Before using imipramine, tell your doctor or pharmacist of all the drugs you are taking and in the event that you have actually some of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation within the EKG), genealogy of certain heart problems (QT prolongation in the EKG, unexpected cardiac death).

Low levels of potassium or magnesium in the bloodstream may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Confer with your doctor about using imipramine properly.

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Before having surgery, tell your doctor or dentist that you are taking this medicine.

This drug will make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.

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To decrease dizziness and lightheadedness, get up slowly whenever increasing from a seated or lying position.

This drug may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

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If you have diabetes, this drug may make it harder to control your blood sugar levels. Check your blood sugar regularly as directed by your doctor. Tell your doctor right away if you have symptoms such as increased thirst/urination, shakiness, unusual sweating, or hunger. Your anti-diabetic medication or diet may need to be adjusted.

Older adults may become more responsive to the side-effects of this drug, especially dizziness (more likely whenever standing up), drowsiness, constipation, trouble urinating, mental/mood changes (such as confusion, agitation) and heart effects such as QT prolongation (see above). Dizziness, drowsiness, and confusion can boost the danger of falling.

Care is recommended when using this drug in children. (See also the Warning section.)

This medication should be utilized only when obviously needed during pregnancy. Infants born to mothers who took comparable medications during pregnancy may have symptoms such as trouble urinating, prolonged sleepiness, shaking, and seizures. Talk about the risks and benefits with your doctor.

Since untreated mental/mood issues (such as despair, anxiety, panic disorders) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

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