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Mestinon (Pyridostigmine) affects chemicals by the body processes that are active in the communication between nerve impulses and muscle movement.

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Pyridostigmine is used to deal with the signs and symptoms of myasthenia gravis. It is also employed in military personnel who had been exposed to nerve gas.

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Pyridostigmine could also be used for purposes unlisted with this medication guide.


Take exactly as prescribed because of your doctor. Do not take in larger or smaller amounts or for over recommended. Follow the directions in your prescription label.

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Take this medicine with food or milk if it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill could potentially cause excessive drug to be released previously.

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Measure liquid medicine with a special dose measuring spoon or medicine cup, not which has a regular table spoon. If you do not possess a dose measuring device, ask your friendly phamacist for one.

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The amount and timing on this prescription medication is vitally important for the success of the treatment. Carefully follow your doctor's instructions about how much medicine to consider and when to take it.

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Your doctor may occasionally make positive changes to dose to successfully obtain the best results. You may be inspired to keep a daily record of once you took each dose and exactly how long the results lasted. This will help your medical professional decide if your dose needs to be adjusted.
If you need surgery, tell the surgeon beforehand that you're using pyridostigmine. You may need to stop while using the medicine for a short time. Store at room temperature away from moisture and heat.

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Take the medicine as prescribed from your doctor.


Keep the tablets inside their original container, with the canister of moisture-absorbing preservative that is included with this medicine.

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Active ingredient: Pyridostigmine

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Side Effects

Get emergency medical help in case you have all of these warning signs of a hypersensitivity: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Stop using pyridostigmine and call a medical expert at the same time in case you have all of these serious unwanted side effects:

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extreme muscle weakness, muscle twicthing;

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slurred speech, vision problems;

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severe vomiting or diarrhea;

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cough with mucus;

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seizure (convulsions); or

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worsening or no improvement within your signs of myasthenia gravis.

Less serious unwanted effects can include:

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cold sweat, pale skin;

urinating more than usual;

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This isn't a complete set of unwanted effects among others may occur. Call your physician for medical health advice about unwanted effects.

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You should avoid using pyridostigmine in case you are allergic into it, or if you possess a bladder or bowel obstruction.

To ensure you can safely take pyridostigmine, tell your doctor in case you have some of these other difficulties:

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kidney disease;

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an ulcer or other serious stomach disorder;

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high blood pressure levels, heart problems;

overactive thyroid; or

a reputation seizures.

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It just isn't known whether pyridostigmine will harm an baby. Tell your doctor if you are pregnant or want to become pregnant while using this medication. It just isn't known whether pyridostigmine passes into breast milk or if it could harm a nursing baby. Do not use medicines without telling your physician in case you are breast-feeding your baby.

Drugs interaction 

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Tell a medical expert about all other medicines you use, especially:

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atropine (Atreza, Sal-Tropine);

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belladonna (Donnatal, and others);

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benztropine (Cogentin);

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clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

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dimenhydrinate (Dramamine);

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methscopolamine (Pamine), scopolamine (Transderm Scop);

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glycopyrrolate (Robinul);

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mepenzolate (Cantil);

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bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators including ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills which contain an antihistamine for example diphenhydramine (Tylenol PM) or doxylamine (Unisom);

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heart rhythm medication for example quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), while others;

irritable bowel medications including dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

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medicine to treat Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

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a steroid like betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

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This list isn't complete and other drugs may interact with pyridostigmine. Tell a medical expert about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your medical professional.

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