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Mestinon (Pyridostigmine) affects chemicals in the body which might be involved in the communication between nerve impulses and muscle movement.

Pyridostigmine can be used to help remedy the symptoms of myasthenia gravis. It is also employed in military personnel who are encountered with nerve gas.

Pyridostigmine may also be used for purposes not listed in this medication guide.

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Take just as prescribed through your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on the prescription label.
Take this medicine with food or milk whether it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause a lot of drug to be sold at one time.

Measure liquid medicine which has a special dose measuring spoon or medicine cup, not having a regular table spoon. If you do not have a very dose measuring device, ask your pharmacist for starters.

The amount and timing on this medicine is extremely important to the success of your treatment. Carefully follow your physician's instructions regarding how much medicine to consider when to adopt it.

Your doctor may occasionally alter your dose to successfully get the best results. You may be inspired to keep a daily record of whenever you took each dose and how long the results lasted. This will help your medical professional determine if your dose must be adjusted.
If you need surgery, tell the surgeon beforehand you are using pyridostigmine. You may need to stop while using medicine for the short time. Store at room temperature faraway from moisture and heat.

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Take the medicine as prescribed from your doctor.


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Keep the tablets of their original container, with the canister of moisture-absorbing preservative that is included with this medicine.

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Active ingredient: Pyridostigmine

Side Effects

Get emergency medical help when you have some of these signs and symptoms of an allergic reaction: hives; lack of breath; swelling of one's face, lips, tongue, or throat. Stop using pyridostigmine and call a medical expert immediately in case you have some of these serious negative effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

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severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, panic attacks;

seizure (convulsions); or

worsening or no improvement in your symptoms of myasthenia gravis.

Less serious unwanted side effects may include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This is just not a complete report on side effects among others may occur. Call a medical expert for health advice about unwanted side effects.

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You should not use pyridostigmine if you are allergic with it, or if you have a bladder or bowel obstruction.

To make sure you can safely take pyridostigmine, tell your doctor for those who have these other concerns:


kidney disease;

an ulcer and other serious stomach disorder;

high blood pressure, heart disease;

overactive thyroid; or

a good seizures.

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It just isn't known whether pyridostigmine will harm an baby. Tell your medical professional if you're pregnant or intend to conceive while using medicines. It is not known whether pyridostigmine passes into breast milk or when it could harm a nursing baby. Do not use medicines without telling a medical expert if you are breast-feeding your baby.

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Drugs interaction 

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Tell your doctor about all the other medicines you have, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, yet others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications including darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators including ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that includes an antihistamine for example diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication like quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;

irritable bowel medications for example dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to take care of Alzheimer's dementia, including donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid for example betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list isn't complete and other drugs may connect to pyridostigmine. Tell a medical expert about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your physician.

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