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INDICATIONS

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Detrol is indicated for the treating overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol the same manner prescribed by your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on the prescription label.

Your doctor may occasionally alter your dose to make sure you acquire the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill could cause excessive drug to be released previously.

Store Detrol at room temperature from moisture as well as heat.

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If you missed a dose - take the missed dose once you remember. Skip the missed dose if it's almost time for your next scheduled dose. Do not take extra medicine to generate inside the missed dose.

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DOSAGE

The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose might be lowered to 2 mg daily based on individual response and tolerability; however, limited efficacy data are available for Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol is not appropriate for used in patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min haven't been studied and employ of Detrol within this population isn't recommended.

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For patients that are taking drugs which are potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and lightweight. Do not store within the bathroom. Keep Detrol out of your reach of children and from pets.

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Side Effects

Get emergency medical help when you have all of these warning signs of a hypersensitivity to Detrol: hives; breathlessness; swelling of your face, lips, tongue, or throat. Stop using Detrol and call your medical professional at the same time in case you have any of these serious negative effects:

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Less serious Detrol unwanted effects can sometimes include:

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This just isn't a complete report on unwanted effects yet others may occur. Call your physician for medical health advice about unwanted side effects.

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Precautions

Before taking tolterodine, tell your medical professional or pharmacist should you be allergic to it; or in case you have every other allergies. This product might have inactive ingredients, that may cause allergic reactions or any other problems. Talk to your pharmacist for additional information.

This medication really should not be used if you have certain medical conditions. Before applying this medicine, consult your medical professional or pharmacist in case you have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), a particular eye condition (uncontrolled narrow-angle glaucoma).

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Before using this medication, tell a medical expert or pharmacist your medical history, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, some muscle disease (myasthenia gravis).

Tolterodine could cause a disorder that affects one's heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat along with other symptoms (including severe dizziness, fainting) which need immediate medical help. The chance of QT prolongation could possibly be increased for those who have certain health conditions or consider other drugs that may affect the center rhythm (see also Drug Interactions section). Before using tolterodine, tell a medical expert or pharmacist when you have these things conditions: certain cardiovascular disease (heart failure, slow heartbeat, QT prolongation within the EKG), family history of certain heart related illnesses (QT prolongation in the EKG, sudden cardiac death).

Low degrees of potassium or magnesium in the blood can also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your medical professional about using tolterodine safely.

This drug could make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that needs alertness or clear vision before you are sure you'll be able to perform such activities safely. Limit booze.

This medication can cause decreased sweating. Avoid becoming overheated in hot weather, saunas, or during exercise or any other strenuous activities since heatstroke may occur.

Kidney function declines while you grow older. This medication is slowly removed by the kidneys. Therefore, older people might be more responsive to this drug.

This medication should be used not until clearly needed when pregnant. It isn't known whether Detrol will harm an child. Tell a medical expert in case you are pregnant or want to become pregnant while applying this medication. Discuss the potential for loss and benefits with a medical expert.

It is unknown if this type of drug passes into breast milk. Consult your medical professional before breast-feeding.

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