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Precautions

Do NOT use Fluoxetine if:

• you are allergic to your ingredient in Fluoxetine

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• you consider or have got a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days

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• you are taking a fenfluramine derivative (eg, dexfenfluramine), an H₁ antagonist (eg, astemizole, terfenadine), nefazodone, pimozide, a serotonin-norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, paroxetine), sibutramine, thioridazine, or tryptophan.

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Contact your physician or physician immediately if all of these sign up for you.

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Some medical ailments may interact with Fluoxetine. Tell your doctor or pharmacist in case you have any health concerns, particularly if any from the following sign up for you:

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• if you might be pregnant, about to get pregnant, or are breast-feeding

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• when you have allergies to medicines, foods, or another substances
• if you or even a member of the family includes a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse

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• if you have a history of seizures, heart disease, liver problems, severe kidney problems, stomach or bowel bleeding, diabetes, or metabolism problems

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• if you'll be having electroconvulsive therapy (ECT).

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Some medicines may connect to Fluoxetine. Tell your medical provider if you take every other medicines, especially any with the following:

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• Anorexiants (eg, phentermine), fenfluramine derivatives (eg, dexfenfluramine), linezolid, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), St. John's wort, trazodone, or tryptophan because severe negative effects, say for example a reaction that could include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur

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• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) as the likelihood of bleeding, including stomach bleeding, could possibly be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) because the chance of low blood sodium levels may be increased
• Tramadol since the likelihood of seizures may be increased

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• Cyclobenzaprine or H₁ antagonists (eg, astemizole, terfenadine) because severe heart related illnesses, including irregular heartbeat, may occur

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• HIV protease inhibitors (eg, ritonavir) given that they may increase the likelihood of Fluoxetine's side effects

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• Aripiprazole, benzodiazepines (eg, alprazolam), beta-blockers (eg, propranolol), carbamazepine, clozapine, dextromethorphan, digoxin, flecainide, haloperidol, hydantoins (eg, phenytoin), lithium, norepinephrine reuptake inhibitors (eg, atomoxetine), phenothiazines (eg, chlorpromazine, thioridazine), pimozide, propafenone, risperidone, tricyclic antidepressants (eg, amitriptyline), or vinblastine as the likelihood of their unwanted side effects could possibly be increased by Fluoxetine.

This might not be a total set of all interactions that could occur. Ask your health care provider if Fluoxetine may talk with other medicines that you simply take. Check together with your physician before starting, stop, or change the dose of any medicine.

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Important safety information:

• Fluoxetine could potentially cause drowsiness or dizziness. These effects could be worse if you get it with alcohol or certain medicines. Take Fluoxetine with caution. Do not drive or perform other possible unsafe tasks and soon you recognize how you reply to it.

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• Check with your doctor when you drink alcohol or use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Fluoxetine; it might enhance their effects. Ask your pharmacist if you have questions on which medicines could cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take a lot more than the recommended dose, alter your dose, or take Fluoxetine for more than prescribed without checking along with your doctor.

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• Children and teenagers who take Fluoxetine may be at increased risk for suicidal thoughts or actions. Adults can also be affected. The risk may be greater in patients who may have had suicidal thoughts or actions inside the past. The risk can also be greater in patients who have had bipolar (manic-depressive) illness, or if themselves members experienced it. Watch patients having Fluoxetine closely. Contact your physician simultaneously if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic and anxiety attacks; or any unusual alteration of mood or behavior occur. Contact the doctor immediately if any warning signs of suicidal thoughts or actions occur.

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• Diabetes patients - Fluoxetine may affect your blood glucose. Check blood glucose levels levels closely. Ask a medical expert prior to deciding to affect the dose of the diabetes medicine.

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• Serotonin syndrome can be a possibly fatal syndrome that could be due to Fluoxetine. Your risk could be greater with Fluoxetine with certain other medicines (eg, MAOIs, SSRIs, "triptans"). Symptoms can include agitation; coma; confusion; excessive sweating; fast or irregular heartbeat; fever; hallucinations; nausea, vomiting, or diarrhea; tremor. Contact your physician at the same time when you have some of these symptoms.

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• Neuroleptic malignant syndrome (NMS) can be a possibly fatal syndrome that could be brought on by Fluoxetine. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your medical professional immediately for those who have any of these symptoms.

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• If your medical professional lets you know to halt taking Fluoxetine, you will need to watch for several weeks before beginning to take certain other medicines (eg, MAOIs, nefazodone, thioridazine). Ask a medical expert when you start to adopt your brand-new medicines after you've stopped taking Fluoxetine.

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• Fluoxetine may rarely create a prolonged, painful erection. This could happen even when you happen to be not having sexual intercourse. If this is not treated straight away, it may result in permanent sexual difficulties such as impotence. Contact your physician straight away if this happens.

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• Fluoxetine contains some from the same ingredients as Prozac, a medicine employed to treat depression along with other mental problems, and Symbyax, medicine employed to treat depression in patients with bipolar disorder. Do not take Fluoxetine if you happen to be also taking Prozac or Symbyax. Discuss any questions or concerns together with your doctor.

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• Use Fluoxetine with caution inside the elderly; they may be more understanding of its effects, especially low blood sodium levels.

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• Caution is recommended when working with Fluoxetine in children; they might be more responsive to its effects, especially increased risk of suicidal thoughts or actions.

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• Fluoxetine ought to be in combination with warning in youngsters; safety and effectiveness in children are not confirmed.

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• Fluoxetine may cause weight changes. Children and teenagers might need regular weight and growth checks when they take Fluoxetine.
• Pregnancy and breast-feeding: Fluoxetine could potentially cause injury to the fetus if it can be used throughout the last 3 months of childbearing. If you get pregnant, get hold of your doctor. You will need to discuss the advantages and risks of using Fluoxetine while you happen to be pregnant. Fluoxetine can be found in breast milk. Do not breastfeed while you are taking Fluoxetine.