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Uses

INDICATIONS

Keppra is utilized to help remedy partial onset seizures in older adults and children who are no less than one month old.

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It is additionally used to treat tonic-clonic seizures in grown-ups and kids who will be at least 6 years, and myoclonic seizures in adults and kids that are at the very least 12 yrs . old.

INSTRUCTIONS

Take Keppra exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your own prescription label.

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Your doctor may occasionally improve your dose to successfully obtain the best results.

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Keppra is normally taken twice each day. Take the medicine concurrently daily. You may take Keppra with or without food.

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Measure liquid medicine with a special dose-measuring spoon or medicine cup, not having a regular table spoon. If you do not use a dose-measuring device, ask your pharmacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill could cause too much of the drug to be removed in the past.

Use Keppra regularly to find the most benefit. Get your prescription refilled before you decide to run out of medication completely.

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Do not stop using Keppra without first conversing with your physician, even if you feel fine. You could possibly have increased seizures in case you stop applying this medicine suddenly. You should use less before you stop the medication completely.

Seizures are often treated which has a combination of different drugs. Use all medications as directed from your doctor. Read the medication guide or patient instructions given each medication. Do not change your doses or medication schedule without a medical expert's advice. .

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Wear a medical alert tag or carry an ID card proclaiming that you take Keppra. Any health care provider who treats you should know that you're taking seizure medication.

To make certain Keppra isn't causing harmful effects, your kidney function might need to be tested. Visit your physician regularly.

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If you missed a dose - consider the missed dose as soon as you remember. Skip the missed dose if it is almost time for your forthcoming scheduled dose. Do not take extra medicine to make inside the missed dose.

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DOSAGE

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Important Administration Instructions

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Keppra emerges orally with or without food. The Keppra dosing regimen is determined by the indication, age group, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.

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When using the oral solution in pediatric patients, dosing is weight-based (mg per kg) utilizing a calibrated measuring device (not really a household teaspoon or tablespoon).

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Keppra tablets needs to be swallowed whole. Keppra tablets should not be chewed or crushed.

Pediatric Patients

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Treatment must be initiated which has a daily dose of 14 mg/kg into two divided doses (7 mg/kg two times a day). The daily dose needs to be increased every two weeks by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the medical trial, the mean daily dose was 35 mg/kg within this generation. The effectiveness of lower doses has not been studied.

Treatment ought to be initiated having a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg twice daily). The daily dose must be increased into two weeks by an increment of 20 mg/kg towards the recommended daily dose of 50 mg/kg (25 mg/kg two tmes a day). If a patient cannot tolerate a regular dose of 50 mg/kg, the daily dose may be reduced. In the clinical study, the mean daily dose was 47 mg/kg within this age bracket.

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Treatment should be initiated using a daily dose of 20 mg/kg into two divided doses (10 mg/kg two tmes a day). The daily dose needs to be increased every 2 weeks by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose could be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

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For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated having a daily dose of 500 mg given as twice daily dosing (250 mg two tmes a day). The daily dose must be increased every two weeks by increments of 500 mg to a maximum recommended daily dose of 1500 mg (750 mg two tmes a day).

For Keppra tablet dosing in pediatric patients weighing over 40 kg, treatment should be initiated using a daily dose of 1000 mg/day given as two times a day dosing (500 mg two tmes a day). The daily dose must be increased every 2 weeks by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice a day).

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Partial Onset Seizures
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In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were confirmed to be effective. Although in a few studies there were a tendency toward greater response with higher dose [see Clinical Studies], a frequent surge in response with additional dose will not be shown.

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Treatment needs to be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Additional dosing increments might be given (1000 mg/day additional every fourteen days) to some maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day are already found in open-label studies for periods of half a year and longer. There is no evidence that doses in excess of 3000 mg/day confer additional benefit.

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Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy

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Treatment should be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage ought to be increased by 1000 mg/day every 14 days on the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day will not be studied.

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Primary Generalized Tonic-Clonic Seizures

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Adults 16 Years And Older
Treatment needs to be initiated which has a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage needs to be increased by 1000 mg/day every 14 days for the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day will not be adequately studied.


Pediatric Patients Ages 6 To < 16 Years

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Treatment ought to be initiated which has a daily dose of 20 mg/kg into two divided doses (10 mg/kg two tmes a day). The daily dose should be increased every 14 days by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses under 60 mg/kg/day will not be adequately studied. Patients with bodyweight ≤ 20 kg should be dosed with oral solution. Patients with bodyweight above 20 kg can be dosed with either tablets or oral solution. Only whole tablets should be administered.

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Adult Patients With Impaired Renal Function
Keppra dosing should be individualized according for the patient's renal function status.

STORAGE

Store Keppra at room temperature far from moisture, heat, and lightweight.

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Side Effects

Get emergency medical help should you have all of these signs of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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Report any new or worsening symptoms to your physician, such as: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor simultaneously in the event you use a serious unwanted effect such as:

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Less serious Keppra negative effects can include:

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This is not a complete set of unwanted effects among others may occur. Tell your medical professional about any unusual or bothersome side effect.

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Precautions

You must avoid using Keppra in case you are allergic to levetiracetam.

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To be sure you can safely take Keppra, tell a medical expert if you have kidney disease or hypertension.

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You could possibly have thoughts about suicide while using this medicine. Tell a medical expert should you have signs and symptoms of depression or suicidal thoughts throughout the first several weeks of treatment, or once your dose is changed.

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Your family or another caregivers should also be alert to changes within your mood or symptoms. Your doctor will need to check you at regular visits.

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FDA pregnancy category C. It isn't known whether Keppra will harm an baby, but creating a seizure when pregnant could harm the two mother along with the baby. Tell a medical expert in the event you are pregnant or plan to get pregnant while by using this medication. Do not start or stop taking Keppra in pregnancy without your physician's advice. Seizure control is essential during pregnancy. The benefit of preventing seizures may outweigh any risks resulting from taking Keppra. Follow a medical expert's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and might harm a nursing baby. You should not breast-feed while you're using Keppra. Do not give prescription drugs to some child devoid of the advice of the doctor. Your child's dose needs depend on age and weight. The child should remain underneath the care of an doctor while applying this medicine.

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Do not stop using Keppra without first speaking with your doctor, although you may feel awesome. You could possibly have increased seizures should you stop using Keppra suddenly. You might need to use less prior to deciding to stop the medication completely.

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You could possibly have thoughts about suicide while taking Keppra. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

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Report any new or worsening symptoms to your medical professional, such as: mood or behavior changes, depression, anxiety, or should you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

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Wear a medical alert tag or carry an ID card stating that you take Keppra. Any medical care provider who treats you need to know that you take seizure medication.

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Keppra may impair your opinions or reactions. Be careful should you drive or do just about anything that needs that you be alert. Tell your doctor if you are pregnant or intend to become pregnant while employing this medication. Do not start or stop taking Keppra during pregnancy without a medical expert's advice. Having a seizure in pregnancy could harm the two mother and the baby. Seizure control is very important during pregnancy along with the advantages of preventing seizures may outweigh any risks presented by using Keppra.

Avoid having a drink. It can increase some of the side effects of Keppra and might could also increase the potential risk of seizures. This medication may impair your opinions or reactions. Be careful should you drive or do anything whatsoever that requires one to be alert.

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