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Uses

INDICATIONS

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Keppra is utilized to treat partial onset seizures in older adults and kids who are no less than 30 days old.
It can also be used to take care of tonic-clonic seizures in adults and children that are no less than 6 years, and myoclonic seizures in older adults and youngsters who're at the very least 12 years.

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INSTRUCTIONS

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Take Keppra the same manner prescribed because of your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions on the prescription label.

Your doctor may occasionally improve your dose to ensure that you receive the best results.

Keppra is often taken twice per day. Take the medicine as well daily. You may take Keppra with or without food.

Measure liquid medicine having a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not have a very dose-measuring device, ask the pharmacist for one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause a lot of drug to be removed in the past.

Use Keppra regularly to have the most benefit. Get your prescription refilled before you decide to run out of medication completely.

Do not stop using Keppra without first speaking with your physician, in case you feel great. You might have increased seizures in the event you stop employing this medicine suddenly. You should use less before you stop the medication completely.

Seizures tend to be treated having a combination of different drugs. Use all medications as directed from your doctor. Read the medication guide or patient instructions given each medication. Do not alter your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card proclaiming that you adopt Keppra. Any health care provider who treats you should know that you adopt seizure medication.

To be certain Keppra just isn't causing harmful effects, your kidney function ought to be tested. Visit your medical professional regularly.

If you missed a dose - take the missed dose whenever you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to generate up the missed dose.

DOSAGE

Important Administration Instructions

Keppra is given orally with or without food. The Keppra dosing regimen is determined by the indication, age group, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with body mass ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with weight above 20 kg.

When while using oral solution in pediatric patients, dosing is weight-based (mg per kg) employing a calibrated measuring device (not a household teaspoon or tablespoon).
Keppra tablets should be swallowed whole. Keppra tablets shouldn't be chewed or crushed.

Pediatric Patients

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Treatment should be initiated which has a daily dose of 14 mg/kg by 50 percent divided doses (7 mg/kg two tmes a day). The daily dose ought to be increased every fourteen days by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg twice a day). In the medical trial, the mean daily dose was 35 mg/kg on this population. The effectiveness of lower doses is not studied.

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Treatment ought to be initiated which has a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice a day). The daily dose must be increased by 50 % weeks by an increment of 20 mg/kg towards the recommended daily dose of 50 mg/kg (25 mg/kg twice a day). If a patient cannot tolerate an everyday dose of 50 mg/kg, the daily dose could possibly be reduced. In the clinical study, the mean daily dose was 47 mg/kg with this generation.

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Treatment needs to be initiated using a daily dose of 20 mg/kg into two divided doses (10 mg/kg two times a day). The daily dose must be increased every two weeks by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). If a patient cannot tolerate a day-to-day dose of 60 mg/kg, the daily dose could be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment must be initiated having a daily dose of 500 mg given as two tmes a day dosing (250 mg two times a day). The daily dose should be increased every two weeks by increments of 500 mg to your maximum recommended daily dose of 1500 mg (750 mg two times a day).

For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment should be initiated using a daily dose of 1000 mg/day given as twice a day dosing (500 mg twice daily). The daily dose should be increased every fourteen days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg two tmes a day).

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Partial Onset Seizures
Adults 16 Years And Older

In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were been shown to be effective. Although in most studies there was a propensity toward greater response with higher dose [see Clinical Studies], a regular rise in response to comprehend dose is not shown.

Treatment needs to be initiated with a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Additional dosing increments could possibly be given (1000 mg/day additional every 2 weeks) to a maximum recommended daily dose of 3000 mg. Doses higher than 3000 mg/day happen to be used in open-label studies for periods of six months and longer. There is no evidence that doses greater than 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment ought to be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage needs to be increased by 1000 mg/day every two weeks on the recommended daily dose of 3000 mg. The effectiveness of doses below 3000 mg/day has not been studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage needs to be increased by 1000 mg/day every 14 days on the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day hasn't been adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment must be initiated having a daily dose of 20 mg/kg into two divided doses (10 mg/kg two tmes a day). The daily dose needs to be increased every two weeks by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses below 60 mg/kg/day will not be adequately studied. Patients with body weight ≤ 20 kg should be dosed with oral solution. Patients with weight above 20 kg might be dosed with either tablets or oral solution. Only whole tablets must be administered.

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Adult Patients With Impaired Renal Function
Keppra dosing must be individualized according for the patient's renal function status.

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STORAGE

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Store Keppra at room temperature from moisture, heat, and lightweight.

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Side Effects

Get emergency medical help in case you have these signs of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to a medical expert, for example: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call a medical expert immediately in the event you possess a serious side effect such as:

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Less serious Keppra unwanted side effects might include:

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This just isn't a complete set of unwanted side effects among others may occur. Tell your medical professional about any unusual or bothersome unwanted effect.

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Precautions

You must avoid using Keppra if you are allergic to levetiracetam.

To make sure you can safely take Keppra, tell your physician in case you have kidney disease or blood pressure.

You could have thoughts about suicide while taking this medicine. Tell your physician in the event you have signs and symptoms of depression or suicidal thoughts during the first several weeks of treatment, or once your dose is changed.

Your family or other caregivers should also be attentive to changes in your mood or symptoms. Your doctor will have to check you at regular visits.

FDA pregnancy category C. It is just not known whether Keppra will harm an baby, but having a seizure when pregnant could harm the two mother and also the baby. Tell your physician if you are pregnant or prefer to conceive while using this medication. Do not start or stop taking Keppra when pregnant without a medical expert's advice. Seizure control is very important while pregnant. The benefit of preventing seizures may outweigh any risks resulting from taking Keppra. Follow your physician's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using Keppra. Do not give prescription drugs to a child minus the advice of your doctor. Your child's dose needs are based on age and weight. The child should remain within the care of the doctor while employing this medicine.

Do not stop using Keppra without first actually talking to your physician, although you may feel great. You might have increased seizures in the event you stop using Keppra suddenly. You ought to use less when you stop the medication completely.

You may have thoughts about suicide while taking Keppra. Your doctor will have to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your medical professional, like: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card on the grounds that you take Keppra. Any health care bills provider who treats you need to know that you adopt seizure medication.

Keppra may impair your opinions or reactions. Be careful in case you drive or do anything whatsoever that requires you to be alert. Tell a medical expert in case you are pregnant or want to conceive while using this medication. Do not start or stop taking Keppra in pregnancy without your medical professional's advice. Having a seizure when pregnant could harm the two mother and also the baby. Seizure control is very important while pregnant and the great things about preventing seizures may outweigh any risks resulting from using Keppra.

Avoid drinking alcohol. It can increase a few of the negative effects of Keppra and may even also increase the potential risk of seizures. This medication may impair your opinions or reactions. Be careful if you drive or a single thing that requires one to be alert.

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