This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing oil that is facialsebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause permanent scarring.

DIFFERENT USES: This section contains uses of this drug which are not listed in the approved labeling that is professional the drug but which will be prescribed by your health care expert. Utilize this drug for a condition which is placed in this section only when it has been so prescribed by your health care professional.

This medication may also be used to treat a type that is certain of (neuroblastoma).

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Read the Medication Guide supplied by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions regarding isotretinoin, consult with your physician or pharmacist before taking the medication.

Swallow capsules whole. Don't crush or chew them. Isotretinoin is often taken twice daily for 15-20 weeks, or as directed by your doctor. Directions for many generic forms of isotretinoin state that it must certanly be taken with dishes. Nevertheless, the FDA has indicated that the Absorica brand name may be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your pharmacist or doctor for lots more information. Take this drug with a glass that is full of, and do not lie down for 10 mins after taking it.

The dosage is founded on your medical condition, weight, and response to treatment.

Your acne may worsen during the first couple of days of using this medication, also it may take up to 1-2 months before you notice the benefit that is full of medication. A second course of treatment may be started after you have stopped taking the drug for 2 months if severe acne returns. The manufacturer will not recommend long-term use of isotretinoin. Do not take more than the recommended dose.

Since this drug may be consumed through the skin and lung area and may harm an baby that is unborn ladies who are pregnant or who could become pregnant should perhaps not handle this medicine or breathe the dust from the capsules.

adverse Effects

Dry lips and mouth, minor inflammation of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of locks may happen. If any of these effects persist or aggravate, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice potato chips, chew (sugarless) gum, drink water, or utilize a saliva substitute.

Keep in mind that the physician has recommended this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have serious side effects.

Tell your physician right away if you have any of these unlikely but adverse that is serious: mental/mood changes (e.g., depression, aggressive or violent behavior, as well as in rare situations, thoughts of committing suicide), tingling feeling in skin, quick/severe sunburn (sunlight sensitivity), back/joint/muscle pain, indications of illness (e.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.

Isotretinoin may hardly ever cause disease associated with the pancreas (pancreatitis) that may seldom be fatal. Stop taking this medication and tell your medical practitioner straight away in the event that you develop: severe stomach pain, severe or persistent nausea/vomiting.

Stop taking this medicine and tell your doctor appropriate away if you develop these unlikely but very serious unwanted effects: serious frustration, vision changes, ringing in the ears, hearing loss, chest discomfort, yellowing eyes/skin, dark urine, severe diarrhea, rectal bleeding.

A very serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you notice any observeable symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Into the US -

Call your doctor for medical advice about negative effects. You might report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your physician for medical advice about side effects. You may report side effects to wellness Canada at 1-866-234-2345.


Before taking isotretinoin, tell your medical professional or pharmacist in the event that you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain ingredients that are inactivesuch as soybean, parabens), which can cause allergy symptoms or other problems. Some people who are sensitive to peanuts may also be allergic to soy. Talk to your pharmacist for additional information.

Anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density) before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders ( e.g..

Do not donate bloodstream after you stop taking it while you are taking isotretinoin and for at least 1 month.

This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective outside.

Isotretinoin make a difference your vision night. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

You may not tolerate them as well as usual while using this medication if you wear contact lenses. Contact your doctor for lots more information.

Don't have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring might occur.

Avoid the employment of alcohol while taking this medication because it might increase the risk of certain side-effects (age.g., pancreatitis).

Limited information shows isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop growth that is normal some children (epiphyseal plate closing). Consult your doctor for more details.

Care is preferred when using this medication into the elderly because they may be more painful and sensitive to its results, especially the impacts on bones.

Care is recommended when using this drug in young ones because they might be more sensitive to its impacts, especially back/joint/muscle pain.

This drug ought not to be used during pregnancy or by those who may become pregnant during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See section that is also warning.

Since this drug may be absorbed through skin and lungs and may harm an unborn baby, ladies that are pregnant or who may become pregnant should not handle this medicine or breathe the dust from the capsules.

You must have two negative pregnancy tests before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is good, you must stop taking this medication and consult your doctor right away.

It is unknown if this medication passes into breast milk. Nevertheless, similar drugs pass into breast milk. Breast-feeding while by using this medication is not advised. Consult your physician before breast-feeding.

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