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Precautions

Do NOT use Coumadin if:

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• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled high blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia

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• you've active serious bleeding, bleeding within the brain, certain circulation problems (eg, aneurysm, dissecting aorta), or inflammation or infection with the heart

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• you've active ulcer or bleeding from the stomach or bowel, urinary tract, genitals, or respiratory tract

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• you might have recently had or will be having eye, brain, or vertebrae surgery; spinal puncture; spinal anesthesia; or any type of major surgery

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• you cannot have routine blood clotting tests
• you are unable to follow your doctor's instructions properly , nor have someone that will help you take your medicine

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• you take mifepristone, streptokinase, or urokinase.

Contact a medical expert or doctor straight away if all of these affect you.

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Some health conditions may communicate with Coumadin. Tell your physician or pharmacist if you have any medical conditions, particularly if any of the following connect with you:

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• should you be planning to become pregnant or are breast-feeding
• in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• if you have a reputation stomach or bowel problems (eg, bleeding, ulcer, inflammation), cardiovascular disease (eg, heart failure, infection), blood clots, anemia or another blood problems (eg, protein C deficiency, high red blood cell levels), circulation problems, or blood pressure

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• if you have a good liver, kidney, or thyrois issues; yellowing of the skin or eyes; mental or mood problems; high cholesterol levels; arthritis; diabetes; or cancer
• for those who have poor nutrition, celiac disease, nutrient or fat absorption problems, or 'abnormal' amounts of vitamin K or vitamin C within the blood, or in the event you consume alcohol
• if you have a fever, bad health, diarrhea, fluid buildup, excessive fat in the stools (steatorrhea), a recent or current infection, or tuberculosis, or should you will probably be exposed to high temperatures for a prolonged duration of time

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Some medicines may talk with Coumadin. Tell your health care provider in case you take another medicines, especially any with the following:

• Heparin and other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), salicylates (eg, aspirin), streptokinase, or urokinase since the probability of bleeding could be increased

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• Mifepristone because excessive bleeding may occur

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• Many prescription and nonprescription medicines (eg, useful for infections, inflammation, discomfort, hypertension, high cholesterol levels, seizures, mental or mood problems, diabetes, stomach or bowel problems, irregular heartbeat, contraception, hormone replacement, cancer, among others), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may communicate with Coumadin, helping the probability of serious side effects like bleeding or blood clots.

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This is probably not a whole report on all interactions that could occur. Ask your medical provider if Coumadin may talk with other medicines which you take. Check with your medical provider before you begin, stop, or affect the dose of any medicine.

Important safety information:

• Tell a medical expert or dentist that you take Coumadin when you get any medical or dental care, emergency care, or surgery.
• Do NOT take greater than the recommended dose or use for longer than prescribed without checking with your physician. Contact your physician right away if you may have taken an excessive amount Coumadin.

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• Do not are drinking alcohol while you are taking Coumadin; it could improve the risk of Coumadin's unwanted effects.
• Do not change you activity level or weight without checking with your doctor; the risk of Coumadin's unwanted side effects may be increased.
• Do not change your diet plan without checking with your medical professional. Eat a normal, balanced diet. Foods who have high degrees of vitamin K (eg, green leafy vegetables, broccoli, liver, certain vegetable oils) may change the effect of Coumadin. Ask your doctor to get a report on foods that could affect Coumadin. Tell your physician if any foods on the list certainly are a section of what you eat.

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• Do not eat cranberry products or drink cranberry juice while you are taking Coumadin. Tell your physician if the products already are a part of what you eat.
• Elevated body temperature may increase the effect of Coumadin. Be careful to avoid becoming overheated, especially during warm weather.

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• Coumadin decreases blood clotting. Use caution while doing activities such as brushing your teeth, flossing, or shaving. Avoid activities which could cause bruising or injury. Seek immediate medical assistance in case you fall or injure yourself. Tell your physician in case you have unusual bruising or bleeding. Tell a medical expert if you have dark, tarry, or bloody stools.
• Do not take aspirin whilst you take Coumadin unless your doctor lets you know to. If you already take aspirin for a heart or any other condition, talk with your doctor about whether or not you should continue to take it with Coumadin.

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• Tell your medical professional in case you will probably be traveling or in case you will be restricted to a bed or chair for a long period of time (eg, car or airplane ride). This may enhance your probability of having a blood clot.

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• If therapy with Coumadin is stopped, the blood thinning effects may last for 2 to 5 days when you stop taking it. Discuss questions or concerns with your physician. Do not suddenly stop taking Coumadin without checking with your medical professional.
• Lab tests, including certain blood clotting tests (eg, PT, INR), might be performed when you use Coumadin. These tests could possibly be accustomed to monitor your trouble or pay attention to negative effects. Be sure to keep all doctor and lab appointments.

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• Use Coumadin with caution in Asian patients; they might be more responsive to its effects, especially bleeding.

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• Use Coumadin with caution in the elderly; they could possibly be more responsive to its effects, especially bleeding.

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• Coumadin needs to be in combination with warning in children; safety and effectiveness in youngsters haven't been confirmed. Children might need more frequent tests when they use Coumadin.

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• If you can become pregnant, you have to make use of an effective kind of birth control while you take Coumadin. If you've got questions regarding effective contraceptive, talk with your medical professional.

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• Pregnancy and breast-feeding: Do not use Coumadin if you are pregnant. It has been consideration to damage the fetus. Avoid pregnancy while you are taking it. If you think you could possibly be pregnant, speak to your doctor without delay. It is not known if Coumadin can be found in breast milk. If you are or will be breast-feeding when you use Coumadin, consult your doctor. Discuss any possible risks in your baby.

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