This medication can be used to avoid or treat gout attacks (flares). Usually gout signs develop instantly and involve just one or a few joints. The toe that is big leg, or ankle joints are usually affected. Gout is caused by too much uric acid in the blood. When uric acid levels into the bloodstream are way too high, the uric acid may form hard crystals in your joints. Colchicine works by decreasing swelling and lessening the create up of the crystals crystals that cause pain into the affected joint(s).

This medication is also utilized to avoid assaults of pain within the abdomen, upper body, or joints caused by a particular inherited disease (familial Mediterranean fever). It really is thought to operate by decreasing the body's production of a protein that is certain A) that builds up in people with familial Mediterranean fever.

Colchicine is not a pain medication and really should maybe not be used to alleviate other factors behind discomfort.

DIFFERENT USES: This area contains uses of this drug that aren't detailed in the approved labeling that is professional the drug but that could be recommended by the health care professional. Use this medication for a condition that is listed in this part only if it has been so recommended by your health care professional.

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This medication may also be used to reduce swelling and inflammation regarding the sac that covers the surface of the heart, an ailment called pericarditis.

How to utilize colchicine

Read the Medication Guide supplied by your pharmacist you get a refill before you start taking colchicine and each time. If you have any relevant concerns concerning the information, ask your medical practitioner or pharmacist.

Take this medication by mouth with or without meals, exactly as directed by your physician. Dosing recommendations vary widely and may vary from the recommendations that are following. Taking more than the recommended dose may not increase this medication's effectiveness that can increase your risk for side effects. Ask your pharmacist or doctor for more details.

If you're taking this medication to treat a gout attack, follow the directions carefully given by your doctor. This medication works best if you take it at the first sign of an attack. The suggested dose is 1.2 milligrams at the sign that is first of attack, followed by 0.6 milligrams one hour later. The maximum recommended dose is 1.8 milligrams taken over a 1-hour period. Ask your physician ahead of time about how soon you can repeat treatment with this particular medicine if another gout is had by you attack.

If you are taking this medication to prevent gout attacks or for pericarditis, ask your doctor about the dose and schedule you should follow. Very carefully follow your doctor's directions.

The usual dose is 1.2 to 2.4 milligrams daily if you are taking this medication to prevent attacks of pain caused by familial Mediterranean fever. The dose that is total be taken once daily or divided into two doses a day. Your doctor might have to adjust your dose to control your symptoms or for those who have side effects.

The dosage is dependant on your condition that is medical drugs/foods you may be taking, and response to treatment. To reduce your risk for serious adverse effects, do not increase your dose, take it more frequently, and take it for a bit longer than directed by your physician. Severe unwanted effects may happen even at typical doses that are prescribed.

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If the physician directs you to definitely take colchicine regularly, use it frequently to obtain the benefit that is most from it. To help you remember, take it at the same time(s) each time.

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Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.

If you are taking this medication to treat symptoms due to familial Mediterranean fever, tell your doctor if your condition does not improve or if it worsens.

Exactly what conditions does colchicine treat?

adverse Effects

Diarrhoea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Understand that your physician has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.

Stop using this medication and get medical help right away if some of these extremely severe unwanted effects happen: unusual bleeding/bruising, severe diarrhoea or vomiting, muscle weakness or pain, numbness/tingling in your fingers or toes, pale or grey color for the lips/tongue/palms of arms, signs of infection (such as for example fever, persistent sore throat), unusual weakness/tiredness, fast heartbeat, shortness of breath, change in the quantity of urine.

A tremendously serious reaction that is allergic this drug is rare. However, seek immediate attention that is medical you notice any symptoms of a critical hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This isn't a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your doctor for medical advice about unwanted effects. You may report adverse effects to FDA at 1-800-FDA-1088 or at

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In Canada - Call your medical practitioner for medical advice about adverse impacts. You may report adverse effects to Health Canada at 1-866-234-2345.

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Record colchicine adverse effects by chance and severity.


Before using this medication, tell your physician or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Communicate with your pharmacist for more details.

Before using this medication, tell your medical professional or pharmacist your history that is medical of: renal problems, liver problems (such as cirrhosis).

Alcohol can decrease this drug's effectiveness. Limit alcohol while using this drug.

This medicine can affect how well your body absorbs some meals and nutrients (such as vitamin B12). Consult your pharmacist or doctor for more details.

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Before having surgery, tell your doctor or dentist about all the products you employ (including prescription drugs, nonprescription drugs, and herbal items).

Older adults may be more sensitive to the relative side-effects of this drug, especially muscle mass weakness/pain and numbness/tingling inside their fingers or toes.

Colchicine can decrease production that is sperm which may influence the power of a male to father a kid. Consult your medical practitioner for more information.

During pregnancy, this medicine should be properly used only once clearly needed. Discuss the risks and benefits with your doctor.

This medicine passes into breast milk. While there have been no reports of damage to nursing babies, consult your medical professional before breast-feeding. Your doctor may recommend you take your medication apart from breast-feeding that you separate the time(s.

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What should I know pregnancy that is regarding nursing and administering colchicine to young ones or the elderly?

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