Clomipramine is used to take care of obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living.

This medication belongs to a class of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.

DIFFERENT USES: This section contains uses with this medication being perhaps not placed in the approved labeling that is professional the drug but which may be prescribed by your health care professional. Use this drug for a condition that is listed in this area only if it is often so prescribed by your health care professional.

This medication has additionally been utilized to treat depression, panic assaults, and ongoing pain.

How exactly to use Anafranil

Read the Medication Guide available from your own pharmacist. Check with your pharmacist or doctor if you have any questions.

Take this medication by mouth with or without meals as directed by your medical professional. To lessen adverse effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Often, the dose that is daily maybe not be more than 250 milligrams for adults and 200 milligrams for kids and teenagers.

Follow your physician's guidelines very carefully. Do not just take pretty much medication or frequently take it more than prescribed. Your condition shall not improve any faster and your threat of side results such as for instance seizures may be increased. Dosage is founded on your medical condition and response to therapy.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.

Utilize this medication regularly in order to obtain the benefit that is most from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.

Do not suddenly stop using this medication without consulting your physician. Some conditions may become even worse when the drug is suddenly stopped. You'll experience sweating, dizziness, nausea, vomiting, headache, or irritability if you instantly stop taking this drug. Your dose may gradually need to be decreased.

It may just take 2 to 3 weeks or longer ahead of the complete aftereffects of this medication are noticed. Inform your doctor if your condition persists or if it worsens.

Side Effects

See also Warning section.

Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily worsen when you initially start taking clomipramine. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To alleviate mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute.

To stop constipation, maintain a diet sufficient in fibre, drink plenty of water, and exercise. If you then become constipated while making use of this drug, consult with your pharmacist for aid in selecting a laxative (age.g., stimulant-type with stool softener).

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

Tell your physician right away if any of these unlikely but adverse that is serious happen: mental/mood modifications (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual periods, muscle mass stiffness, ringing within the ears, sexual issues (e.g., reduced sexual ability, alterations in desire), shakiness (tremors), numbness/tingling of the hands/feet, trouble urinating.

Tell your doctor straight away if any of these rare but extremely serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially regarding the tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and rarely cause a very condition that is serious serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Get medical help right away in the event that you have very severe part effects, including: black stools, upper body discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights at night).

A tremendously serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially of this face/tongue/throat), severe dizziness, trouble breathing.

This is simply not a list that is complete of adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In america -

Call your doctor for medical advice about adverse effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about negative effects. You could report effects that are side Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your medical practitioner or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain inactive ingredients, which can cause allergies or other problems. Talk to your pharmacist for additional information.

Before applying this medication, tell your doctor or pharmacist your health background, especially of: blood dilemmas (e.g., purpura, thrombocytopenia), breathing problems (e.g., asthma, chronic bronchitis), individual or family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, renal problems, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very serious a reaction to certain medicines (neuroleptic malignant syndrome), heartburn/stomach acid within the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may boost your threat of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, mind injury/disease), particular kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can hardly ever cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention immediately.

The threat of QT prolongation could be increased in the event that you have certain medical conditions or are taking other drugs that could cause QT prolongation. Before using clomipramine, inform your physician or pharmacist of all the drugs you are taking of course you have some of the next conditions: certain heart related illnesses (heart failure, slow heartbeat, QT prolongation in the EKG), family reputation for certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the bloodstream may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your medical practitioner about making use of clomipramine safely.

This drug will make you dizzy or drowsy or cause temporary vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit beverages that are alcoholic.

To diminish dizziness and lightheadedness, get up slowly when rising from a seated or position that is lying.

Before having surgery, tell your dentist or doctor that you're taking this medication.

Care is recommended when utilizing this drug in children whom be involved in active sports as it might increase the risk of heart problems. (See also the Warning section.)

Older grownups may be more delicate to your relative side-effects of this medication, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when obviously needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or adverse effects. Tell your doctor immediately in the event that you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood issues (such as obsessive compulsive disorder, depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This drug passes into breast milk and may even have undesirable effects on a nursing baby. Consult your doctor before breast-feeding.

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