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Ginette-35 can be used for oral contraception in women who require anti-androgen therapy. Cyproterone acetate can be employed in conjunction with ethinyl oestradiol to the control over idiopathic hirsutism.
For the treating acne that is severe, especially androgen-dependent acne associated with inflammation, seborrhoea or the formation of nodes.
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Before commencing with Ginette-35, an appropriate medical (including gynaecological) examination carried out and the patient's medical history carefully evaluated. Regular medical examinations are recommended during use. Pregnancy ought to be excluded.
Disorders from the clotting system and genealogy of thrombo-embolic diseases, especially in a young age, ought to be excluded.
Androgen-producing tumours or an adrenal enzyme defect should be ruled out before prescribing Ginette-35 for the management of hirsutism.
Additional contraceptive precautions should be taken for that first two weeks with the first cycle or if a tablet is accidentally missed.
Spotting may occur and often will usually stop spontaneously.
The patient is recommended to talk her doctor if prolonged and persistent bleeding occurs.
The tablet needs to be taken roughly simultaneously daily, not exceeding one day, for max effectiveness. The tablet might be taken having a meal to lessen nausea.
Missed doses: Take immediately, that is within the next 12 hours on the latest, although not when it's nearly time to the next dose. Do not double doses. Take the next tablet on the usual time to prevent withdrawal bleeding. Additional non-hormonal contraceptive precaution needs to be taken.
In the case of diarrhoea or vomiting, additional non-hormonal contraception should be used in order to avoid pregnancy.
First cycle: The patient should take the first tablet about the first day of the cycle (the first day from the cycle being day one with the menstrual bleeding). Thereafter, one tablet needs to be taken daily, following the sequence of the arrows, as well, until all of the tablets are already taken. The first tablet ought to be removed from the silver section (of the calender pack), commencing with the appropriate day as indicated on the strip.
Subsequent cycles: A new pack must be started the very next day after completing the first sort pack, once more beginning with the appropriate day inside the silver section with the strip. This method must be followed as long as the contraception is desired.
For the treatments for androgen-dependent acne: Dosage in terms of contraception.
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Take exactly as prescribed.
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Store Ginette-35 below 86 degrees F (30 degrees C). Store far from heat, moisture, and light. Do not store within the bathroom. Keep Ginette-35 out with the reach of kids and far from pets.
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Woman who use oral contraceptives needs to be strongly advised never to smoke. Smoking raises the risk of myocardial infarction.
Women smoking over 15 cigarettes per day have at least a 20% increased chance of serious cardiovascular side-effects. This risk also increases as we grow old and is also quite marked ladies over 35 yrs . old.
Not to supply in kids and men.
Do not use if:
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Oral contraceptives must not be utilized during known or suspected pregnancy as it can cause severe harm to the foetus.
A combination oral contraceptive mustn't be prescribed from a recent evacuation of the hydatidiform mole until urine and plasma gonadotropin concentrations have returned to normal.
Hypersensitivity to the in the ingredients.
Known or suspected breast cancer.
Patients with liver diseases or malignant or wasting diseases.
It should not be given to patients using a history of thrombo-embolic disorders. This may include myocardial infarction, pulmonary embolism, venous thrombosis and stroke.
Contra-indicated in patients with severe chronic depression and sickle-cell anaemia.
Oral contraceptives are contra-indicated in patients with oestrogen-dependent neoplasms, functional ovarian cysts, the Dubin-Johnson or Rotor syndromes, disorders of lipid metabolism, markedly impaired liver function, cerebrovascular insufficiency, heart disease, thrombophlebitis, deteriorating otosclerosis, a history of pruritus during previous pregnancy, undiagnosed vaginal bleeding, herpes, recurrent cholestatic jaundice or porphyria.
Patients with classical migraine must avoid using a combination oral contraceptive.
Relative contra-indications (these patient would require medical supervision):
Diabetes mellitus, tetany, hypertension, epilepsy, chorea, multiple sclerosis, renal dysfunction, asthma, mental depression, blue veins, cardiac dysfunction, gallbladder disease, patients who wear disposable lenses and obese patients, or another conditions affected by fluid retention. The risk benefits needs to be considered in patients with endometriosis and uterine fibroids. It is suggested how the usage of Ginette-35 be discontinued if any in the following symptoms occur:
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