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Uses

INDICATIONS

Imuran can be used to prevent rejection of an transplanted kidney. It is probably the gang of medicines called immunosuppressive agents. Azathioprine will lower your body's natural immunity in patients who receive transplants to prevent rejection in the new kidney. It is also utilized to relieve joint and swelling for patients with arthritis rheumatoid.

INSTRUCTIONS

Use this medicine just as directed because of your doctor. Do not take a greater portion of it, or a reduced amount of it, than your doctor ordered. Taking excessive might increase the probability of uncomfortable side effects, and taking weak hands won't help your problem.

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This drugs are sometimes given as well as other medicines. If you are utilizing several medicines together, make sure you realize how to bring them in daytime. Ask your doctor that may help you plan a way to make sure to take your medicines in the right times.

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Do not stop investing in this medicine without first checking with a medical expert.

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Imuran sometimes causes feeling sick. Taking this medicine after meals or at bed time may lessen stomach upset. Talk to your doctor when you have questions or continue to have issues with nausea / vomiting.

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If you miss a dose with this medicine, go on it at the earliest opportunity. However, if it is almost time for your upcoming dose, skip the missed dose and get back on your regular dosing schedule. Do not double doses.

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DOSAGE

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The dose on this medicine will change for various patients. Follow your physician's orders or even the directions about the label. The following information includes merely the average doses of this medicine. If your dose is different, do not change it unless your physician tells you to take action.

The volume of medicine which you take depends around the strength of the medicine. Also, the quantity of doses you're taking every day, the time allowed between doses, and the time period you take the medicine depend around the problem that you can are using the medicine.

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For oral dosage form (tablets):

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For kidney transplant rejection:

For rheumatoid arthritis: 

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STORAGE 

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Store the medicine in a closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.

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Keep out in the reach of kids.

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Do not keep outdated medicine or medicine will no longer needed.

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Ask your medical practioner how you should eliminate any medicine you tend not to use.

Side Effects

Along using its needed effects, medicine could cause some unwanted side effects. Although not most of these unwanted side effects may occur, whenever they happen they might need medical attention.

Check with a medical expert immediately if any of the following unwanted side effects occur:


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Incidence not known

Some unwanted side effects may occur have a tendency to usually do not need medical assistance. These side effects may go away during treatment as the body adjusts towards the medicine. Also, your overall health care professional might be able to tell you about ways to avoid or reduce some negative effects. Check along with your health care professional if any in the following side effects continue or are bothersome or in case you have any questions about them:

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More common
Nausea or vomiting (mild)
swollen joints
Incidence not known
Hair loss or thinning with the hair

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Other negative effects unlisted could also appear in some patients. If you notice another effects, check along with your medical practioner.

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Call your physician for medical advice about negative effects.

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Precautions

If you will be taking this medicine for some time, it's very important that your medical professional check you at regular visits for almost any problems or unwanted effects which might be due to this medicine. Blood tests may be needed to test for unwanted effects.

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Using this medicine while you're pregnant can harm your unborn baby. Use an effective form of birth control method to keep from having a baby. If you think you might have become pregnant while using the this medicine, tell your medical professional straight away.

Do not make use of this medicine if you are also taking mercaptopurine (Purinethol®). Using these medicines together might lead to serious uncomfortable side effects.

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If you are using azathioprine for arthritis, ensure a medical expert knows if you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to take care of your arthritis inside past. Using azathioprine after these medicines may raise your risk for unwanted side effects. Talk to your doctor for those who have questions on this.

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This medicine may improve your risk of getting certain types of cancer, especially from the skin, lymph system (lymphoma), or blood (leukemia). Talk to a medical expert in case you have concerns relating to this risk.

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Use sunscreen or sunblock lotions with a sun protection factor (SPF) for at least 15 frequently when you might be outdoors. Wear protective clothing and hats, and remain beyond direct sunlight between your hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

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While you happen to be receiving treatment with azathioprine, and after you stop treatment by using it, usually do not have any immunizations (vaccines) without your doctor's approval. Azathioprine may decrease your body's resistance as well as the vaccine may not act as well or you'll have the infection the vaccine is meant to stop. In addition, you shouldn't be around other persons moving into your household who receive live virus vaccines since there is an opportunity they could pass the herpes simplex virus on you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get all-around them and tend not to stay inside the same room with them for days on end. If you have questions regarding this, talk to your physician.

Azathioprine can temporarily lower the number of white blood cells within your blood, increasing the possibility of getting disease. It can also lower the number of platelets, that happen to be necessary for proper blood clotting. If this occurs, there are certain precautions you are able to take, especially when your blood count is low, to cut back the chance of infection or bleeding:

Check with a medical expert without delay if you have multiple of the symptoms while you are utilizing this medicine: severe queasiness; diarrhea; fever; rash; a general sense of discomfort or illness; muscle or joint pain; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of an serious reaction on the medicine with your bowel (intestine).

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Do not take other medicines unless they are discussed with your physician. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

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