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ARAVA is indicated in adults for the management of active rheumatoid arthritis symptoms (RA):


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more frequently, and don't take on it for a longer period than your physician ordered.

The dose with this medicine will change for various patients. Follow your medical professional's orders or the directions for the label. The following information includes exactly the average doses of this medicine. If your dose is different, tend not to change it unless your doctor notifys you to do so.

The amount of medicine that you simply take depends around the strength with the medicine. Also, the amount of doses you take daily, time allowed between doses, and also the time period you take the medicine depend on the disease for which you are utilizing the medicine.

For oral dosage form (tablets):

For rheumatoid arthritis symptoms:

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If you miss a dose of the medicine, take it as quickly as possible. However, whether it is almost time for your forthcoming dose, skip the missed dose and return to your normal dosing schedule. Do not double doses.

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Store at 25°C (77°F); excursions permitted 15-30°C (59-86°F). Protect from light. Keep out from the reach of children. Do not keep outdated medicine or medicine no more needed. Store the medicine in the closed container at room temperature, far from heat, moisture.

 Keep out of the reach of youngsters. Do not keep outdated medicine or medicine will no longer needed. Store the medicine in a closed container at room temperature, from heat, moisture.

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Side Effects

Stop by using this medicine and look with your physician right away if you're having burning, numbness, tingling, or painful sensations inside the arms, hands, legs, or feet. These could be signs of a condition called peripheral neuropathy.

Adverse reactions associated with the usage of leflunomide in RA include diarrhea, elevated liver enzymes (ALT and AST), alopecia and rash.

Along having its needed effects, medication could cause some unwanted effects. Although not all of these unwanted effects may occur, should they happen they might need medical attention.

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Check with a medical expert immediately if any with the following unwanted effects occur:

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Some side effects may occur that usually tend not to need medical attention. These negative effects might go away during treatment because your body adjusts to the medicine. Also, your wellbeing care professional could possibly let you know about approaches to prevent or reduce many of these side effects. Check using your health care professional if any of the following unwanted effects continue or are bothersome or if you might have any queries about them:
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Other unwanted side effects not listed could also occur in some patients. If you notice every other effects, check together with your medical practioner.

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It is vital that your physician look at the progress at regular visits to make sure that this medicine is in working order. Blood tests may be needed to evaluate for negative effects.

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Using this medicine when you are pregnant damages your developing fetus. Use an effective form of birth control to help keep from conceiving. If you think you might have become pregnant when using the medicine, tell your doctor right away.

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Leflunomide can also cause birth defects in the event the father is applying it when his sexual partner becomes pregnant. Men taking leflunomide should use condoms being a form of contraception during intercourse. A man aiming to father a kid should stop taking this medicine and appearance together with his doctor straight away.

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Serious skin reactions can take place with this medicine. Stop by using this medicine and appearance with your physician straight away if you might have any from the following symptoms while investing in this medicine: blistering, peeling, or loosening with the skin; chills; itching; joint or muscle pain; red lesions on the skin, often having a purple center; sores, ulcers, or white spots inside the mouth or about the lips; or unusual tiredness or weakness.

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Liver problems may occur while you are employing this medicine. Stop using this medicine and appearance with a medical expert right away if you're having multiple of the symptoms: abdominal or stomach pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; loss in appetite; feeling sick; skin rash; swelling with the feet or legs; unusual tiredness or weakness; or yellow eyes or skin.

Leflunomide can temporarily lower the number of white blood cells with your blood, increasing the chance of getting contamination. It can also lower the number of platelets, that happen to be required for proper blood clotting. If this occurs, there are specific precautions you can take, specially when your blood count is low, to lessen potential risk of infection or bleeding:

Check with your medical professional straight away if you might have a cough with or without a fever, difficulty breathing, or any risk with breathing.

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You needs to have a skin test for tuberculosis prior to starting by using this medicine. Tell your medical professional should you or anyone inside your home has ever endured a positive response to a tuberculosis test.

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Using this medicine may raise your risk of getting serious infections or cancer. Talk to your medical professional if you might have concerns concerning this risk.

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Do not take other medicines unless they've been discussed with your physician. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or nutritional vitamins.

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