Methotrexate is used to treat certain kinds of cancer or to control psoriasis that is severe rheumatoid arthritis that has not responded to other treatments. It may also be used to control rheumatoid arthritis that is juvenile. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the system that is immune.
Early remedy for rheumatoid arthritis with more aggressive therapy such as for instance methotrexate assists to lessen further joint harm and to preserve function that is joint.
OTHER USES: This section contains uses of this drug which are not listed in the approved labeling that is professional the drug but that will be prescribed by your health care pro. Make use of this medication for a condition which is placed in this part as long as this has been therefore prescribed by your health care professional.
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This medication doubles for lupus and psoriatic arthritis.
Read the Patient Information Leaflet if available from your pharmacist before you start taking methotrexate and each time you get a refill. If you have any relevant questions, ask your doctor or pharmacist.
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Methotrexate is a medication that is strong. The dosage and how often you take this medication are based on your condition that is medical and to treatment. There are many dosing that is different for this medication (especially for cancer treatment). Therefore, it is vital that you follow your doctor's instructions carefully. Take this medicine by lips as directed by your doctor.
For the treating psoriasis or rheumatoid arthritis, just take this medication by mouth as directed by your medical professional, usually when a week. It might take up to a few months before you have the benefit that is full of drug.
Usually do not increase your dose or use this drug more often or for longer than prescribed. Your condition shall not improve any faster, and your risk of side effects will increase.
Since this drug is absorbed through the skin and lungs and may even harm an unborn baby, women who are pregnant or who may conceive must not handle this medication or breathe the dirt from the tablets.
Drink lots of fluids while taking this medication unless your doctor informs you otherwise. Doing so assists your kidneys to get rid of the medication from your system and give a wide berth to a few of the relative negative effects.
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See section that is also warning.
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Sickness, nausea, stomach pain, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist immediately.
Temporary hair loss may occur. Normal new hair growth should return after treatment has ended.
Remember that the doctor has recommended this medicine she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious side effects.
Tell your physician right away if you have adverse that is serious, including: lips sores, diarrhea, signs of anemia (such as for example unusual tiredness, pale skin), indications of liver issues (such as for example dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone pain, unusual discomfort and discoloration of your skin, modification in the amount of urine, dry coughing, muscle weakness.
Get help that is medical away if you have got any extremely severe negative effects, including: weakness on one part of this body, neck stiffness, severe headache, vision changes, irregular heartbeat, mental/mood changes, seizures.
This medication might lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, coughing).
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This medication can impact sperm production, a result that may reduce male fertility. Consult your doctor for more details.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any observeable symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is simply not a complete list of possible adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.
Into the US -
Call your medical professional for medical advice about negative effects. You'll report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to wellness Canada at 1-866-234-2345.
See section that is also warning.
Before taking methotrexate, tell your physician or pharmacist if you have any other allergies if you are allergic to it; or. This product may contain ingredients that are inactive which can cause sensitive responses or other issues. Talk to your pharmacist for additional information.
Before by using this medication, inform your physician or pharmacist your health background, particularly of: liver condition, kidney infection, lung disease (such as for example pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders, stomach/intestinal diseases (such as for example peptic ulcer, ulcerative colitis), any active illness (including chickenpox or current exposure to it), folic acid deficiency.
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Methotrexate make you more prone to get infections or may worsen any current infections. Consequently, clean your hands well to stop the spread of infection. Avoid contact with individuals who have infections that may spread to other people (such as chickenpox, measles, flu). Consult your medical professional when you have been subjected to an infection or even for more details.
Usually do not have immunizations/vaccinations without the consent of your doctor. Avoid experience of those who have recently received vaccines that are livesuch as flu vaccine inhaled through the nose).
To lower the chance of getting cut, bruised, or injured, use caution with razor-sharp objects like razors and nail cutters, and give a wide berth to tasks such as for instance contact sports.
This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid alcoholic beverages.
Before having surgery, tell your physician or dental practitioner about all the products you use (including prescription drugs, nonprescription medications, and herbal products).
This medicine may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Methotrexate must not be used during maternity. It could harm an unborn baby. It is important to prevent pregnancy during and after treatment with methotrexate. Therefore, males and females must use reliable forms of birth control (such as condoms, birth control pills) during treatment. Males should continue to use birth control for at least 3 months after the final end of treatment. Females should continue to use contraception for at minimum 1 cycle that is menstrual the end of treatment. If you become pregnant or think you may be pregnant, tell your doctor right away.
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Since this drug can be consumed through the epidermis and lungs and may harm an baby that is unborn women who are pregnant or who may get pregnant should perhaps not handle this medication or inhale the dust through the tablets.
Methotrexate passes into breast milk and may harm a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Check with your doctor before breast-feeding.
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