See section that is also warning.
This medication is used to take care of certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a medication that is psychiatricanti-psychotic type) that actually works by helping to restore the balance of specific normal substances (neurotransmitters) in the brain.
Clozapine decreases hallucinations and helps prevent committing suicide in individuals who tend to try to harm themselves. It will help one to think more clearly and favorably about your self, feel less nervous, and be a part of everyday life.
If you are utilizing the liquid form of the medication, read the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and any time you get a refill. For those who have any relevant questions, pose a question to your doctor or pharmacist.
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Simply take this medication by mouth with or without food, as directed by your doctor. If you're taking the tablets that dissolve in the mouth, remove each tablet carefully from the blister pack immediately before taking your dose. Allow the tablets to dissolve on your swallow and tongue. There is no need to take the dissolving tablets with water. Discard any dissolving tablets that were previously subjected to air due to opened/damaged packaging. Do not save your self them for the next dose.
If you work with the liquid form of this medication, shake the bottle well for 10 seconds before each use. Carefully measure the dose using a measuring device/spoon that is special. Do not use a family group spoon because you may not obtain the dose that is correct.
You will need to begin taking this drug at a low dose, increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Follow your doctor's instructions exactly. Your dosage is based on your condition that is medical and to treatment. Since clozapine can cause a decrease in white blood cells, you shall need to get blood tests done regularly as directed. Be sure to keep all appointments of these laboratory tests. (See also Notes section.)
If you miss your doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose you were on (see Missed Dose section). Use this medication regularly in order to get the benefit that is most from it. To help you keep in mind, use it at the same time(s) each day.
Do not stop taking clozapine without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Also, you might experience symptoms such as severe sweating, headache, sickness, vomiting, and diarrhoea. To prevent these signs while you might be stopping therapy with this medication, your medical professional may lower your dosage slowly. Consult with your pharmacist or doctor for more details. Report any new or worsening symptoms right away.
It may take many weeks ahead of the benefit that is full of medication takes effect. Inform your physician if for example the condition persists or worsens.
See section that is also warning.
Drooling, drowsiness, dizziness, headache, shaking (tremor), vision problems (e.g., blurred vision), weight gain, and constipation may occur. Many of these effects (especially drowsiness) lessen as your body gets used to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
To prevent constipation, keep a diet adequate in fiber, drink plenty of water, and workout. If you become constipated when using this drug, consult with your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.
This medication may make your blood rarely sugar level rise, which can cause or worsen diabetes. Rarely, very serious conditions such as diabetic coma may occur. Tell your medical practitioner straight away if you develop symptoms of high blood glucose, such as increased thirst and urination. In the event that you already have diabetic issues, make sure to always check your blood sugars regularly. Your physician might need certainly to adjust your diabetes medication, exercise program, or diet.
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This medication could also cause weight that is significant and a growth in your cholesterol (or triglyceride) levels. These effects, along side diabetes, may increase your risk for developing heart condition. Talk about the dangers and advantages of therapy with your physician.
Tell your physician right away if you have any serious side effects, including: facial/muscle twitching, seizures, uncontrollable movements.
Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, mental/mood changes, trouble breathing with workout, sudden weakness, pain/redness/swelling of the arms/legs, persistent nausea/vomiting, stomach/abdominal pain, yellowing of eyes/skin.
This medicine may hardly ever cause a tremendously condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away if you have of the following symptoms: temperature, muscle mass stiffness/pain/tenderness/weakness, severe tiredness, serious confusion, sweating, fast/irregular heartbeat, dark urine, improvement in the amount of urine.
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An extremely serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic consist of: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing.
This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your medical practitioner for medical advice about side impacts. You may report effects that are side Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about adverse effects. You may possibly report effects that are side Health Canada at 1-866-234-2345.
See also Warning and adverse Effects sections.
Before using clozapine, inform your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which may cause allergy symptoms or other problems. Confer with your pharmacist for more information.
Before using this medication, tell your physician or pharmacist your medical history, specially of: history of bloodstream disorders (such as leukemia, low white blood cell count), bowel problems (such as paralytic ileus, cranky bowel syndrome ), difficulty in breathing, diabetes/family history of diabetes, high cholesterol/triglyceride levels, glaucoma, heart problems, renal problems, liver problems, obesity/family history of obesity, seizures, difficulty urinating (such as prostate problems).
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Clozapine may cause an ailment that impacts the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other signs (such as for example serious dizziness, fainting) that need medical attention appropriate away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that will impact the heart rhythm. Before making use of clozapine, tell your medical professional or pharmacist of most the drugs you take and if you have any of the following conditions: certain heart issues (heart failure, sluggish heartbeat, QT prolongation in the EKG), genealogy and family history of certain heart related illnesses (QT prolongation into the EKG, unexpected cardiac death).
Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about utilizing clozapine safely.
This drug could make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit alcoholic beverages.
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Tell your physician because you may be at a higher risk for a drop in your white blood cells if you are a descendent of Ashkenazi Jews.
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Before having surgery, tell your doctor or dentist that you will be making use of this medicine.
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Liquid services and products or dissolving tablets may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised you to limit/avoid these substances in your diet if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires. Ask your pharmacist or doctor about by using this product safely.
Older grownups may be more sensitive to the relative part aftereffects of this medication, specially constipation, dizziness, and QT prolongation (see above). Dizziness can raise the risk of falling.
During maternity, this medication should be used only when clearly needed. Babies born to moms who purchased this medication over the past 3 months of maternity may rarely develop signs muscle that is including or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their month that is first the doctor straight away.
Since untreated mental/mood problems (such as for example schizophrenia, schizoaffective disorders) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.
This medicine may pass into breast milk and also have undesirable effects on a nursing infant. Breast feeding is not advised while taking clozapine. Consult your doctor before breast-feeding.
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