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INDICATIONSLevodopa is converted to a chemical called dopamine (DOE pa meen) inside brain. Symptoms of Parkinson's disease may be a result of low levels of dopamine inside the brain.

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Carbidopa aids in preventing the breakdown of levodopa before it could attain the brain and take effect.

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The combination of carbidopa and levodopa is employed to deal with Parkinson symptoms including muscle stiffness, tremors, spasms, and poor muscle control. This medication is additionally used to treat Parkinson symptoms brought on by carbon monoxide poisoning or manganese intoxication.

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Carbidopa and levodopa could also be used for other purposes not listed with this medication guide.


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If you happen to be already taking levodopa (Larodopa, Dopar), you have to stop taking it a minimum of 12 hours prior to starting taking carbidopa and levodopa.

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Take exactly as prescribed from your doctor. Do not take in larger or smaller amounts or for more than recommended. Follow the directions on the prescription label.

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Carbidopa and levodopa may be taken with or without food. Take your doses at regular intervals to keep a comfortable level of the drug within you all the time.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill could cause too much of the drug to be released previously.

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The regular tablet can be broken or crushed as needed to make it easier to swallow.

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To make orally disintegrating tablet (Parcopa):

Keep these days in their blister pack until you might be ready to go ahead and take medicine. Open the package and peel back the foil from named blister. Do not push a tablet through the foil otherwise you damages the tablet.

Using dry hands, remove the tablet make it in your mouth. It will start to dissolve without delay.

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Do not swallow the tablet whole. Allow it to dissolve within your mouth without chewing. Swallow several times as the tablet dissolves.

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It may take as much as many weeks of employing carbidopa and levodopa before your symptoms improve. For best results, keep while using the medication as directed. Talk with your doctor if the symptoms tend not to improve after a couple of weeks of treatment. Also educate doctor if the effects of this medication seem to wear off quickly among doses.

To be certain this prescription medication is helping your trouble and is not causing harmful effects, your blood will need to be tested often. Your heart, liver, and kidney function might also need to be tested. Visit a medical expert regularly.

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This medication can cause unusual results with certain tests. Tell any doctor who treats you that you are using carbidopa and levodopa.

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Store at room temperature away from moisture, heat, and light-weight.

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Side Effects

You may realize that your sweat, urine, or saliva appears dark in color, including red, brown, or black. This is not a harmful side effect, nevertheless it could potentially cause staining of the clothes or bed sheets.

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Get emergency medical help in case you have all of these indications of an allergic reaction: hives; lack of breath; swelling of the face, lips, tongue, or throat. Call a medical expert at the same time in case you have these serious negative effects:

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restless muscle movements in your eyes, tongue, jaw, or neck;

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worsening of tremors (uncontrolled shaking);

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high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling like you might pass out;

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seizure (convulsions);

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painful or difficult urination;

severe nausea, vomiting, or diarrhea;

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uneven heartbeat or fluttering within your chest;

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confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;

chest pain or heavy feeling, pain spreading on the arm or shoulder.

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Less serious negative effects may include:

mild nausea, dry mouth, loss of appetite, heartburn, diarrhea, constipation;

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headache, dizziness, drowsiness, blurred vision;

sneezing, stuffy nose, cough, and other cold symptoms;

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This is not a complete listing of side effects and others may occur. Call your physician for health advice about negative effects.


Do not take carbidopa and levodopa in case you have used an MAO inhibitor for example isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the past fourteen days. Serious, life-threatening side effects can occur with carbidopa and levodopa prior to MAO inhibitor has cleared from your body. 

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You must not take this medication if you're allergic to carbidopa (Lodosyn) or levodopa (Larodopa), or when you have:

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narrow-angle glaucoma;

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unusual lesions on the skin who have not been checked by the doctor; or

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a good malignant melanoma (melanoma).

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If you have any of these other difficulties, you need a dose adjustment or special tests:

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heart disease, hypertension, coronary artery disease, a heart rhythm disorder, or a prior heart attack;

asthma, chronic obstructive pulmonary disease (COPD), and other breathing disorder;
liver or kidney disease;

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an endocrine (hormonal) disease;

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a stomach or intestinal ulcer;

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wide-angle glaucoma; or

depression or other mental illness.

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Carbidopa and levodopa could cause you to drift off during normal daytime activities including working, talking, eating, or driving. You may go to sleep suddenly, even though feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.

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You may have increased sexual urges, unusual urges to gamble, or any other intense urges while taking carbidopa and levodopa. It is not known whether the medicine actually causes this effect. Talk with your doctor if you believe you have any intense or unusual urges while taking carbidopa and levodopa.

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Some people taking medicines for Parkinson's disease are suffering from cancer of the skin (melanoma). However, individuals with Parkinson's disease could have a and the higher chances than a lot of people for developing melanoma. Talk to your physician about your specific risk and what skin symptoms to watch for. You may need to have regular skin exams.

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FDA pregnancy category C. It is not known whether carbidopa and levodopa will harm an developing fetus. Tell your medical professional if you are pregnant or intend to get pregnant with all the medicines. Carbidopa and levodopa may pass into breast milk and may harm a nursing baby. Do not use this medication without telling a medical expert if you're breast-feeding a child.

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The disintegrating tablet (including Parcopa) could have phenylalanine. Talk to your doctor before employing this kind of carbidopa and levodopa when you have phenylketonuria (PKU).

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If you missed the dose go on it when you remember. Skip the missed dose when it is almost time for your forthcoming scheduled dose. Do not take extra medicine to create up the missed dose.

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