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Uses

INDICATIONS

Motilium is indicated for:

- delayed gastric emptying of functional origin with gastro-oesophageal reflux and/or dyspepsia;

- charge of nausea and vomiting of central or local origin;

- just as one anti-emetic in patients receiving cytostatic and radiation therapy;

- facilitates radiological examination of the top gastro-intestinal tract.

INSTRUCTIONS

Use Motilium as directed because of your doctor.

Take Motilium by mouth before meals.
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If you miss a dose of Motilium, take it as quickly as possible. If it is almost time for your next dose, skip the missed dose and return to your family dosing schedule. Do not take 2 doses simultaneously.

DOSAGE

Acute conditions (mainly nausea, vomiting, hiccup)

Adults: Two tablets (20 mg) three to four times per day, 15 to half an hour before meals and, if needed, before retiring.
Children 5 to 12 years of age: One tablet (10 mg) three or four times daily, 15 to 30 minutes before meals and, if needed, before retiring.

Chronic conditions (mainly dyspepsia)

Adults: One tablet (10 mg) taken 3 x every day, 15 to 30 minutes before meals and, as appropriate, before retiring. The dosage could possibly be doubled.
Children 5 to 12 years: ½ tablet (5 mg) three to four times daily, 15 to 30 minutes before meals and as appropriate, before retiring.

This formulation isn't suited to children under the age of 5 years, but for this gang of patients the suspension can be obtained. Motilium tablets are not suited to children weighing less than 35kg.

Motilium ought to be used in combination with caution in patients with renal impairment or in those prone to fluid retention. In patients with severe renal insufficiency ( serum creatinine greater than 6 mg/100 mL, ie. over 0,6 mmol/L) the elimination half-life of domperidone was increased from 7,4 to 20,8 hours. The dosing frequency should be reduced to a few times daily, according to the severity of impairment, along with the dose should be reduced. Patients on prolonged therapy must be reviewed regularly.

Ask your medical provider any queries you may have about how to work with Motilium.

STORAGE

Store Motilium between 68 and 77 degrees F (20 and 25 degrees C). Protect from heat, light, and moisture. Do not store within the bathroom. Keep Motilium out from the reach of youngsters and faraway from pets.

MORE INFO:

Active Ingredient: Domperidone.

Motilium tablets contain lactose and may be unsuitable if you have lactose intolerance, glucose/galactose malabsorption or perhaps a genetic disorder ultimately causing accumulation of galactose inside blood (galactosaemia).

Side Effects

Medicines as well as their possible unwanted effects can affect individual people differently. The following are a few of the side effects that are considered linked to this medicine. Just because a complication is stated here doesn't imply that all people by using this medicine get each year that or any side effect.

Rare (affect between 1 in 1000 and one in 10,000 people)

Increased level of prolactin (milk producing hormone) in the blood (hyperprolactinaemia). Sometimes this leads to symptoms such as abnormal enlargement of breasts that face men (gynaecomastia), abnormal production of breast milk in males and some women, or stopping of menstrual periods ladies.
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Decreased sexual libido in men.

Very rare (affect lower than one in 10,000 people)

Stomach cramps.
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Diarrhoea.
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Itchy nettle-type rash (urticaria).
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Abnormal or uncontrolled movements of the hands, legs, face, eyes, neck or tongue, for example tremor, twitching or stiffness (extrapyramidal effects). Consult a doctor instantly you may notice any symptoms like this.
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Allergic reaction.

This just isn't a complete set of all unwanted effects which could occur. If you've questions regarding negative effects, contact your health care provider.

Precautions

Do NOT use Motilium if:

you might be allergic to any ingredient in Motilium
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you happen to be pregnant, intending to get pregnant, or get pregnant while taking Motilium
you might be breast-feeding.
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Contact your physician or physician without delay if some of these affect you.

Some medical ailments may connect to Motilium. Tell a medical expert or pharmacist if you have any health concerns, particularly if any from the following connect with you:

if you happen to be pregnant, planning to conceive, or are breast-feeding
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if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
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if you have allergies to medicines, foods, or any other substances.
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Not to be used in

Cancer with the pituitary gland causing over-creation of the hormone prolactin (prolactinoma).
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Conditions where stimulating movement with the stomach may be harmful, for example if you find bleeding, an abnormal hole (perforation) or perhaps a blockage in the stomach or intestines.
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Decreased liver function.
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Some medicines may connect to Motilium. Tell your medical provider if you happen to be taking every other medicines. The following medicines may oppose the stimulating effect of domperidone for the gut and so could make it less capable:

antimuscarinic medicines, including antispasmodics (eg atropine, hyoscine, propantheline), medicines for urinary incontinence (eg oxybutynin, flavoxate, tolterodine, propiverine, trospium), or antimuscarinics for Parkinson's (eg procyclidine, trihexyphenidyl, orphenadrine)
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strong opioid painkillers, eg morphine, codeine.
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This may not be a total set of all interactions that could occur. Ask your doctor if Motilium may interact with other medicines that you take. Check with your medical provider prior to starting, stop, or alter the dose of the medicine.

Important safety information:

Always inform your medical professional if you happen to be pregnant or arranging a pregnancy, before using any medicine.

The safety of the medicine for use when pregnant has not been established. It should not be used in pregnant women unless the opportunity benefits to mom outweigh any risks towards the developing baby. It should only be utilized if the prescription medication is considered essential from your doctor.
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This medicine passes into breast milk in tiny amounts that aren't expected to be harmful to a nursing infant. However, the medicine isn't recommended for use in females who are breastfeeding unless the possibility benefit to the mother outweighs any risks on the nursing infant.
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