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Eldepryl is indicated as an adjunct in the treatments for Parkinsonian patients receiving treatment with levodopa/carbidopa who exhibit deterioration inside the quality of the reply to this therapy.

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Take this medicine only as directed through your doctor. Do not take more of it, don't take on it more frequently, and do not take on it much more time than your physician ordered.

It is most beneficial to look at this medicine before breakfast and without liquids.

If you are using the disintegrating tablet, make sure your hands are dry prior to deciding to handle named. Do not open the blister pack which has named until you are ready to go on it. Remove the tablet from the blister pack by peeling back the foil, then taking today out. Do not push the tablet over the foil. Do not break or split today. Place these days for the top of your tongue, where it will melt quickly. Do not eat food or drink liquids for 5 minutes before or after taking this medicine.

If you miss a dose of the medicine, get it immediately. However, when it is almost time for your forthcoming dose, skip the missed dose and return to your regular dosing schedule. Do not double doses.


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The dose of the medicine changes for various patients. Follow your physician's orders or even the directions on the label. The following information includes only the average doses of this medicine. If your dose differs, don't change it out unless your physician informs you for this.

The amount of medicine that you simply take depends for the strength from the medicine. Also, the amount of doses you are taking on a daily basis, some time allowed between doses, and the time period you adopt the medicine depend on the condition for which you're while using medicine.
For oral dosage form (tablets):
For Parkinson's disease:


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Store the medicine in the closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of kids.
Do not keep outdated medicine or medicine no longer needed.


Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly described within the clinical and pharmacological literature as l-deprenyl.

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Side Effects

Along with its needed effects, medication may cause some unwanted side effects. Although not all of these side effects may occur, when they occur they could need medical assistance.

Check with your physician immediately if the following unwanted effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements with the body
increased sensitivity with the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if getting up from the lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling stuff that are certainly not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside the hands, feet, or lips
puffing from the cheeks
rapid or worm-like movements in the tongue
restlessness or need to keep moving
severe stomach pain
shakiness inside the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation from the mouth
tightness inside the chest
trembling or shaking with the hands or feet
twisting movements from the body
uncontrolled chewing movements
uncontrolled movements with the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material seems like coffee grounds

Get emergency help immediately if the following signs of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure level
severe spasm where the head and heels are bent backward and also the body arched forward
troubled breathing

Some unwanted side effects may occur very often usually do not need medical attention. These side effects may go away during treatment as your body adjusts towards the medicine. Also, your health care professional might be able to inform you of approaches to prevent or reduce some of these side effects. Check with your health care professional if any of these unwanted effects continue or are bothersome or if you might have any queries about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

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Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning with the lips, mouth, or throat
dryness or soreness in the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing within the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing with the eyelids
unusual feeling of well-being
unusual weight loss
voice changes

Other unwanted side effects unpublished can also happen in some patients. If you notice some other effects, check with your healthcare professional.

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It is critical that your medical professional look at progress at regular visits to allow for alterations in your dose also to look for any unwanted side effects.

Do not take selegiline if you've got used meperidine (e.g., Demerol®) or perhaps an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 2 weeks. If you do, you could possibly develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high temperature, higher than normal blood pressure levels, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you are applying this medicine. Using these medicines together can cause unwanted side effects.

Selegiline could cause serious unwanted side effects when used as well as some antidepressants. Tell your medical professional if you've got used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past fourteen days.

When selegiline is taken at doses of 10 mg or less each day for that management of Parkinson's disease, there aren't any restrictions on food or beverages you eat or drink. However, the chance exists that dangerous reactions, for example sudden high blood pressure levels, may occur if doses above those employed for Parkinson's disease are taken with foods, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for at least fourteen days once you stop investing in this medicine, these foods, beverages, and also other medicines may continue to react with selegiline if it was used doses greater than those usually employed for Parkinson's disease.

Check with your doctor or hospital hospital immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you are investing in this medicine. These may be symptoms of a serious side effect which should have a very doctor's attention.

Dizziness, lightheadedness, or fainting may occur, especially when you obtain up from the lying or sitting position. Getting up slowly can help. If the problem continues or gets worse, consult your physician.

Selegiline could potentially cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt pieces of ice within your mouth, or work with a saliva substitute. However, in case your mouth is constantly feel dry in excess of 14 days, check using your medical professional or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

It is essential that your physician check your skin for melanoma (tumor) regularly if you might have Parkinson's disease.

Do not stop investing in this medicine without first checking with your medical professional. Your doctor may wish that you reduce gradually the amount you happen to be taking before stopping completely.

Hallucinations may appear in some patients. This is more widespread with elderly patients. If you have hallucinations, seek advice from your medical professional.

Some people who have used this medicine had unusual modifications in their behavior. Talk with your doctor should you start having problems with gambling or increased sexual libido while employing this medicine.

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