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This medication is used to treat movement disorders brought on by Parkinson's disease. It does not cure Parkinson's disease, but it may enhance shakiness (tremor), muscle stiffness, loss of normal motion as your dose of other Parkinson's medicine wears down (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may enhance your range of ability and motion to walk, dress, and exercise. Selegiline is usually used in conjunction with other medicines (e.g., levodopa, carbidopa).

Selegiline is an enzyme blocker (MAO inhibitor) that works by slowing the break down of certain natural substances in the brain (neurotransmitters such as for example dopamine, norepinephrine, and serotonin).

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Take this medicine by mouth, usually twice day-to-day with lunch and breakfast. Taking selegiline late in the day may cause trouble sleeping. Dosage is founded on your medical condition and response to therapy. Do not increase your dose or take it more often than directed.

After you have been taking selegiline for 2 or 3 days, your doctor may direct you to lower your levodopa dose. Follow your physician's instructions closely. Never stop or change the dose of any of your medications without first talking along with your doctor.

It could take a weeks that are few the complete great things about the drug to be noticed. Don't stop taking this drug without first consulting your doctor. Talk to your physician if the medicine stops working well or if your condition worsens.

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Dizziness, abdominal pain, dry mouth, nausea, stomach upset, difficulty sleeping, and headache may occur. If some of these effects persist or worsen, notify your doctor or pharmacist promptly.

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If you are also taking levodopa, you may experience more adverse effects from the levodopa when taking selegiline. Tell your doctor right away if any of these adverse effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your medication or dose. Usually do not stop or change the dose of your levodopa without talking with your doctor first.

Keep in mind that your medical practitioner has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.

Some people taking selegiline have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some full cases, sleep occurred without any emotions of drowsiness beforehand. This sleep effect may occur anytime during treatment with selegiline even although you have used this medication for a time that is long. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities. Your risk of this sleep effect is increased by using liquor or other medications that can allow you to drowsy. See also Precautions area.

Tell your physician right away when you yourself have any adverse that is serious, including: fainting, lack of balance, mental/mood changes (age.g., agitation, confusion, depression, hallucinations), unusual strong urges (such as increased gambling, increased intimate urges), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), bloated ankles/legs, difficulty urinating, uncommon fat gain, easy bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.

This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug and food interactions can increase this danger. (See also Drug Interactions section.) Get medical help right away if some of these serious side effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, serious nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision modifications (age.g., double/blurred vision), sudden sensitivity to light (photophobia).

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This medicine may increase serotonin and rarely cause a tremendously serious condition called serotonin syndrome. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away in the event that you develop some associated with following signs: hallucinations, uncommon restlessness, loss in coordination, fast heartbeat, severe dizziness, unexplained fever, severe nausea/vomiting/diarrhea, twitching muscle.

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A very severe allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a severe allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This isn't a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Phone your doctor for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about adverse effects. You may report adverse effects to Health Canada at 1-866-234-2345.


Before taking selegiline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which trigger allergic reactions or other problems. Confer with your pharmacist for lots more details.

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Before using this medication, tell your medical professional or pharmacist your medical history, particularly of: a particular sort of adrenal gland tumefaction (pheochromocytoma), cerebrovascular infection (age.g., stroke), heart related illnesses (e.g., congestive heart failure, coronary arrest), bleeding problems, history of severe/frequent headaches, peptic ulcer, diabetes, personal/family history of mental/mood disorders (e.g., schizophrenia, bipolar disorder), personal/family reputation for hypertension, liver illness, overactive thyroid (hyperthyroidism).

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This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages that are alcoholic. See also Part Effects section.

To reduce dizziness while the threat of fainting, get up slowly when rising from a sitting or position that is lying.

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Before having surgery, tell your dentist or doctor you are taking this medication. You might need to stop taking this drug beforehand. Follow your physician's directions carefully.

Selegiline is used only when obviously required during maternity. Discuss the risks and benefits along with your doctor.

It is really not known if this medication passes into breast milk. Consult your physician before breast-feeding.

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