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Uses

INDICATIONS

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Prandin (repaglinide) is surely an oral diabetes medicine that assists control blood sugar levels. This medication lowers blood sugar levels by creating the pancreas to generate insulin.

Prandin is used along with eating and working out to take care of diabetes type 2 symptoms. Other diabetes medicines are occasionally employed in conjunction with repaglinide as needed.

Prandin may aso be used for purposes unpublished in this medication guide.

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INSTRUCTIONS  

Take Prandin the same manner prescribed by your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions in your prescription label.

Prandin is often taken three to five times daily, within thirty minutes before eating meals. Follow your medical professional's instructions. If you skip lunch, do not take your dose of Prandin. Wait until the next meal.

Your blood sugar levels will have to be checked often, and you may need other blood tests your doctor's office. Visit a medical expert regularly.

Know the signs of low blood glucose (hypoglycemia) and the ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar available in case you have the signs of low blood sugar levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and can't eat or drink, make use of an injection of glucagon. Your doctor can provide you with a prescription for the glucagon emergency injection kit and show you how you can supply the injection.

Also watch for signs of blood glucose that is excessive (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight-loss.

Check your blood sugar levels carefully throughout a duration of stress or illness, in the event you travel, exercise more than usual, are drinking alcoholic beverages, or skip meals. These things can impact your blood sugar levels and your dose needs can also change.

Your doctor may want one to stop taking Prandin for the short time should you get sick, have a very fever or infection, or if you've surgery or a medical emergency.

Ask a medical expert the best way to adjust your Prandin dose as needed. Do not change your medication dose or schedule without a medical expert's advice.

Prandin is merely part of a total program of treatment this includes diet, exercise, and weight control. Follow your diet, medication, and workout routines very closely. Changing these factors can impact your blood sugar levels.

Use Prandin regularly to have the most benefit. Get your prescription refilled before you run out of drugs completely.

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DOSAGE 

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Active ingredient: Repaglinide

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Repaglinide can be a white to off-white powder with molecular formula C27 H36 N2 O4 plus a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet provides the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and two mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.

 

 

Side Effects

Weight gain, diarrhea, and joint pain may occur. If some of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your medical professional has prescribed this medication while he or she gets judged that the benefit to you is more than the chance of negative effects. Many people using this medication don't have serious side effects.

Repaglinide may cause low blood sugar (hypoglycemia) especially should you consider other medicines for diabetes. Consuming large volumes of alcohol, to not get enough calories from food, or doing unusually heavy exercise could also lead to low blood sugar. Symptoms can include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling with the hands or feet, or hunger. It is a good habit to handle glucose tablets or gel to treat low blood glucose levels. If you don't have these reliable forms of glucose, raise your blood glucose levels quickly when you eat an instant source of sugar such as white sugar, honey, candy, or drinking a glass of veggie juice or non-diet soda. Check with your physician or pharmacist to find out list of positive actions in the event you miss lunch.

Symptoms of high blood glucose (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your physician immediately. Your doctor might need to adjust your diabetes medication(s).

A very serious hypersensitivity to the drug is rare. However, seek immediate medical attention if you notice any in the following symptoms of a serious allergic reaction: rash, itching/swelling (especially with the face/tongue/throat), severe dizziness, trouble breathing.

This is not an entire list of possible negative effects. If you notice other effects unlisted above, contact your physician or pharmacist.

 

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Tell your doctor about all other medications you utilize, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate for example phenobarbital (Solfoton);

heart or hypertension medication including diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), while others;

HIV/AIDS medicine for example delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), among others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication including carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), among others.

You might be more likely to have hyperglycemia (high blood glucose) should you take Prandin with other drugs that raise blood sugar levels, like:

isoniazid;

diuretics (water pills);

steroids (prednisone while others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid among others);

birth control pills and other hormones;

seizure medicines (Dilantin yet others); and

diet pills or medicines to take care of asthma, colds or allergies.

You might be more likely to have hypoglycemia (low blood glucose) in case you are taking other drugs that lower blood sugar, like:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, yet others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, yet others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists usually are not complete there a wide range of other medicines that may increase or minimizing the effects of Prandin on reducing your blood sugar. Using certain medicines causes it to be tougher for you to tell when you might have low blood glucose levels. Tell a medical expert about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling your physician.

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Precautions

Do not use Prandin should you are allergic to repaglinide, if you've type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin). You should not use Prandin as well as gemfibrozil (Lopid) or NPH insulin (such as isophane insulin).

Before taking repaglinide, tell a medical expert or pharmacist in the event you are allergic with it; or if you've any other allergies. This product could have inactive ingredients, which may cause allergies or another problems. Talk to your pharmacist for more details. 

Before using prescription drugs, tell your physician or pharmacist your track record, especially of: kidney disease, liver disease.

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision before you are sure you'll be able to perform such activities safely.

Limit alcohol while taking prescription drugs because it can increase potential risk of developing low blood sugar levels.

During times during the stress, like fever, infection, injury, or surgery, it might be tougher to regulate your blood sugar levels. Consult your doctor because increased stress might require changing your treatment solution, medications, or blood glucose testing.

During pregnancy this medication should supply only if clearly needed. Pregnancy might cause or worsen diabetes. Discuss a strategy with your doctor for managing your blood glucose when pregnant. Your doctor may make positive changes to diabetes treatment during your pregnancy. Discuss the risks and great things about different treatments (such as diet, exercise, and medications including insulin).

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FDA pregnancy category C. It is not known whether Prandin will harm an baby. Tell your doctor in the event you are pregnant or plan to become pregnant while using the Prandin. It is not known whether repaglinide passes into breast milk or if it can be bad for a nursing baby. You should not breast-feed while you take Prandin.

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