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Uses

INDICATIONS

Micronase (Glyburide) is surely an oral diabetes medicine which enables control glucose levels.

Glyburide is utilized to treat type 2 diabetes.

This drugs are not for treating type 1 diabetes.

Glyburide could also be used for other purposes unlisted on this medication guide.

INSTRUCTIONS

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Take just as prescribed from your doctor. Do not take in larger or smaller amounts and for longer than recommended. Follow the directions on the prescription label. Your doctor may occasionally change your dose to ensure that you obtain the best results.

Take glyburide together with your first meal for the day, unless a medical expert lets you know otherwise.

Your blood glucose must be checked often, and you might need other blood tests at your doctor's office. Visit your medical professional regularly.
Know the indications of low blood glucose (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar accessible in case you have the signs of low blood glucose levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you've got severe hypoglycemia and should not eat or drink, readily injection of glucagon. Your doctor can provide a prescription for the glucagon emergency injection kit and tell you how to provide the injection.

Also await signs of blood sugar which is way too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight reduction.

Check your blood glucose levels carefully during a duration of stress or illness, should you travel, exercise more than usual, consume alcohol, or skip meals. These things can affect your blood sugar levels along with your dose needs can also change.

Your doctor may want you to definitely stop taking glyburide for a limited time should you get ill, have a very fever or infection, or if you've got surgical procedures or a medical emergency.
Ask your physician how to adjust your glyburide dose as needed. Do not make positive changes to medication dose or schedule without your medical professional's advice.

If you can find any modifications in the emblem, strength, or type of glyburide you have, your dosage needs may change. Always check your refills to successfully have received the proper logo and form of medicine prescribed from your doctor.

DOSAGE

Take as prescribed because of your doctor.

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STORAGE

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Store at room temperature, protected from moisture, heat, and light.

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Active ingredient: Glyburide

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Side Effects

Stop using glyburide and obtain emergency medical help if you've got all of these warning signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking medicines and call your physician immediately if you have any of these serious side effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots through your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted effects can sometimes include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete report on side effects yet others may occur. Call a medical expert for health advice about unwanted side effects.

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Precautions

You must avoid using medicines should you are allergic to glyburide, or:

should you are undergoing treatment with bosentan (Tracleer);

if you might have type 1 diabetes; or

in the event you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

To make sure you can safely take glyburide, tell your physician if you've got all of these other difficulties:

hemolytic anemia (too little red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

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liver or kidney disease;

in case you are allergic to sulfa drugs; or

if you have been using insulin or taking chlorpropamide (Diabinese).

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Certain oral diabetes medications may enhance your probability of serious heart disease. However, not handling your diabetes can harm your heart and other organs. Talk to your medical professional about the risks and benefits of handling your diabetes with glyburide.

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FDA pregnancy category C. It is not known whether glyburide will harm an child. Similar diabetes medications have caused severe hypoglycemia in babies whose mothers had used the medication close to the time of delivery. Tell your medical professional should you are pregnant or plan to become pregnant when using prescription drugs. It is not known whether glyburide passes into breast milk or if it may harm a nursing baby.

Do not use prescription drugs without telling a medical expert should you are breast-feeding an infant. Older adults could be very likely to have low blood glucose levels while taking glyburide.

 

Important safety information:

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You should avoid using prescription drugs if you are allergic to glyburide, if you are being treated with bosentan (Tracleer), if you might have type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

Before taking glyburide, tell your medical professional if you are allergic to sulfa drugs, if you've been using insulin or chlorpropamide (Diabinese), or if you might have hemolytic anemia (too little red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care not to let your blood sugar get too low. Low blood sugar (hypoglycemia) can occur in case you skip a meal, exercise to much time, are drinking alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you might have low blood glucose levels. Other sugar sources include orange juice and milk. Be sure your household and pals know how you can direct you towards an unexpected emergency.

Drug interactions

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Tell a medical expert about other medications you have, especially:

a blood thinner such as warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor like enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), yet others; or

an antibiotic for example ciprofloxacin (Cipro), levofloxacin (Levaquin), yet others.

Using certain medicines causes it to be more difficult for one to tell when you might have low blood sugar. Tell your medical professional in case you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers like atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.

You could be prone to have hyperglycemia (high blood glucose levels) should you take glyburide with:

isoniazid;

diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid while others);

birth control pills and also other hormones;

heart or blood pressure level medications (Cartia, Cardizem, Nifedical, Covera, Verelan, while others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, yet others);

seizure medicines (Dilantin yet others); and

diet pills or medicines to treat asthma, colds or allergies.


You might be prone to have hypoglycemia (low blood glucose) in the event you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure levels medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or another salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, while others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists usually are not complete and you can find many other medicines that will increase or decrease the effects of glyburide on lowering your blood glucose. Tell your doctor about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling a medical expert.

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