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Micronase (Glyburide) can be an oral diabetes medicine that helps control blood glucose levels.

Glyburide is utilized to deal with diabetes type 2.

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This drugs are not for treating type 1 diabetes.

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Glyburide could also be used for other purposes unpublished within this medication guide.


Take just as prescribed from your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions in your prescription label. Your doctor may occasionally alter your dose to successfully get the best results.

Take glyburide together with your first meal of the day, unless your medical professional lets you know otherwise.

Your blood sugar levels will need to be checked often, and you may need other blood tests at a medical expert's office. Visit your medical professional regularly.

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Know the warning signs of low blood glucose (hypoglycemia) and the ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

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Always keep a supply of sugar for sale in case you've got signs of low blood glucose levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, make use of an injection of glucagon. Your doctor can present you with a prescription to get a glucagon emergency injection kit and let you know how you can provide the injection.

Also look for signs and symptoms of blood sugar levels that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully within a period of stress or illness, should you travel, exercise more than usual, are drinking alcoholic beverages, or skip meals. These things could affect your blood sugar along with your dose needs could also change.

Your doctor might want that you stop taking glyburide for the limited time in case you become ill, have a fever or infection, or if you might have surgery or a medical emergency.
Ask your medical professional how to adjust your glyburide dose if required. Do not change your medication dose or schedule without your medical professional's advice.

If you can find any adjustments to the company, strength, or sort of glyburide you utilize, your dosage needs may change. Always check your refills to ensure that you have received the best brand name and kind of medicine prescribed from your doctor.

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Take as prescribed because of your doctor.

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Store at room temperature, shielded from moisture, heat, and light-weight.

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Active ingredient: Glyburide

Side Effects

Stop using glyburide and have emergency medical help if you have all of these signs and symptoms of an allergic reaction: hives; breathlessness; swelling of your face, lips, tongue, or throat. Stop taking this medication and call a medical expert at the same time if you've some of these serious unwanted side effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

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headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

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Less serious unwanted effects may include:

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mild nausea, heartburn, feeling full;

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This is not a complete listing of unwanted side effects while others may occur. Call a medical expert for medical health advice about negative effects.

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You must avoid using medicines in case you are allergic to glyburide, or:

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should you are undergoing treatment with bosentan (Tracleer);

if you've type 1 diabetes; or

if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

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To be sure to can safely take glyburide, tell your physician if you have all of these other conditions:

hemolytic anemia (deficiencies in red blood cells);

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an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

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a nerve disorder affecting bodily functions;

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liver or kidney disease;

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in case you are allergic to sulfa drugs; or

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if you've been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may raise your likelihood of serious cardiovascular disease. However, not taking care of your diabetes damages your heart and other organs. Talk to your medical professional concerning the risks and great things about your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an baby. Similar diabetes medications have caused severe hypoglycemia in babies whose mothers had used the medication near the period of delivery. Tell a medical expert in case you are pregnant or want to conceive with all the prescription drugs. It is not known whether glyburide passes into breast milk or if it may harm a nursing baby.

Do not use prescription drugs without telling your physician should you are breast-feeding a baby. Older adults could possibly be very likely to have low blood sugar levels while taking glyburide.


Important safety information:

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You should not use medicines in the event you are allergic to glyburide, should you are being treated with bosentan (Tracleer), if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

Before taking glyburide, tell a medical expert if you are allergic to sulfa drugs, if you've got been using insulin or chlorpropamide (Diabinese), or if you've hemolytic anemia (an absence of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

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Take care never to let your blood glucose get too low. Low blood glucose levels (hypoglycemia) can take place in the event you skip a meal, exercise to much time, are drinking alcoholic beverages, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you have low blood glucose. Other sugar sources include orange juice and milk. Be sure your household and close friends know the way to help you in an emergency.

Drug interactions

Tell your medical professional about all other medications you have, especially:

a blood thinner for example warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

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disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor for example enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others; or

an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), and others.

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Using certain medicines makes it tougher for you to tell when you might have low blood sugar levels. Tell a medical expert should you use any of the following:

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albuterol (Proventil, Ventolin);

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clonidine (Catapres);

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reserpine; or

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beta-blockers such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.

You may be more likely to have hyperglycemia (high blood glucose) should you take glyburide with:


diuretics (water pills);

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steroids (prednisone among others);

phenothiazines (Compazine while others);

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thyroid medicine (Synthroid while others);

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birth control pills and also other hormones;

heart or hypertension medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, while others);

seizure medicines (Dilantin among others); and

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diet pills or medicines to treat asthma, colds or allergies.

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You might be very likely to have hypoglycemia (low blood sugar levels) if you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or hypertension medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

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aspirin or other salicylates (including Pepto-Bismol);

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sulfa drugs (Bactrim, Gantanol, Septra, yet others);

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a monoamine oxidase inhibitor (MAOI); and

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other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

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These lists aren't complete and you can find many other medicines that will increase or minimizing the effects of glyburide on lowering your blood sugar. Tell a medical expert about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your medical professional.


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