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Uses

INDICATIONS

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Meldonium treats heart ischemia and its particular consequencesis.  It is utilized in the treatment of brain circulation disorders. Meldonium is assumed to enhance Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was designed to boost Athletic Training & Competitive Performance at the same time as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, with respect to the prescribed dose, is widely used for the treating different heart and vascular diseases, also as for the improvement of work capacity of healthy people at mental and physical overloads and during rehabilitation period.

INSTRUCTIONS

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g each day

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divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, the therapy is repeated in 2-3 weeks.

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• Athletes should take 500 mg – 1 g two times a day before training. Duration of

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treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

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• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) daily, utilizing the whole dose at one time or dividing for two takings. Course of treatment is 4-6 weeks.

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• Cardialgia contrary to the background of dyshormonal myocardiodystrophy – 500 mg daily. Course of treatment is 12 days.

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• Disturbed cerebral circulation. In treatment after elimination of acute disorders: 500 mg – 1 g daily, using whole dose at one time or dividing it for two main takings. In case of chronic disorders: 500 mg per day. General course of treatment is 4-6 weeks. Recurrent courses (usually 2-3 times 12 months) could possibly be taken after consulting a doctor.

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• Diseases of peripheral arteries. 500 mg two times a day.

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• Abstinence syndrome in the event of chronic alcoholism. 500 mg 4 times a day. Course of treatment is 7-10 days.

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• Maximum daily dose is 2000 mg.

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Please talk to your physician prior to employing this or another vitamins and minerals or medications.

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DOSAGE

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Please consult a physician in connection with required dosage.

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Overdosage

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There isn't data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep away from direct sunlight.

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Keep locked and far from children.

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Store in dry place at room temperature.

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Do not exceed storage temperature above 25 C

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Side Effects

Rarely - allergies (redness, rash, itching, oedema), at the same time as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

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Hypersensitivity, increased intracranial pressure (in violation with the venous outflow, intracranial tumors).

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Restrictions:

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Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy haven't been determined.

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Pregnancy and breast-feeding:

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Not recommended while pregnant (safety weren't proven). At the time of treatment should stop breastfeeding (known whether the breast milk gets).

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Interaction with other drugs and other kinds of interaction

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The drug may be coupled with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible growth and development of mild tachycardia and arterial hypotension, care must be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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