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Promethazine is within a gaggle of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. Promethazine also acts being an antihistamine. It blocks the consequences in the natural chemical histamine in your body.

Promethazine is employed to help remedy allergic reactions such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine is not to be used in treating signs of asthma, pneumonia, and other lower respiratory tract infections.


Take promethazine the same manner prescribed through your doctor. Do not take it in larger amounts and for longer than recommended. Follow the directions in your prescription label.

Your doctor may occasionally make positive changes to dose to ensure that you acquire the best comes from this medication.

Promethazine could be taken with or without food or milk.

Measure liquid medicine having a marked measuring spoon or medicine cup, not with a regular table spoon. If you tend not to use a dose-measuring device, ask the pharmacist for one.

Call your doctor if your symptoms tend not to improve, or if they become worse while taking promethazine.

This medication could cause one to have unusual results with certain tests. Tell any doctor who treats you that you are using promethazine.

Seek emergency medical attention if you think you have used which is not this medicine. Overdose symptoms may include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as being prescribed through your doctor.


Store promethazine at room temperature far from moisture, heat, and light.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you've some of these signs and symptoms of a hypersensitivity: hives; lack of breath; swelling of the face, lips, tongue, or throat. Stop using promethazine and call your physician simultaneously if you've some of these serious unwanted side effects:

twitching, or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulties with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might distribute;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing of the skin or eyes);

urinating less than usual or not at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy pores and skin; or

slow heartbeat, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine side effects can include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing within your ears;

weight gain, swelling with your hands or feet;

impotence, trouble having an orgasm; or


This just isn't a complete set of side effects yet others may occur. Tell your medical professional about any unusual or bothersome side-effect.


Stop using promethazine and call your medical professional at once if you've twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early indications of dangerous negative effects. Promethazine may cause unwanted effects that could impair your notions or reactions. Be careful should you drive or a single thing that will require one to be awake and alert. Avoid alcohol consumption, which may increase some with the unwanted side effects of promethazine. There are many other medicines that can connect to promethazine. Tell your medical professional about each of the prescription and over-the-counter medications you employ. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not start using a new medication without telling a medical expert. Keep a list along of every one of the medicines you have and show this list to your doctor or another physician who treats you.

Important safety information:

Promethazine should not be provided to a child younger than a couple of years old. Promethazine can cause severe breathing problems or death in a kid younger than 2. Carefully follow your medical professional's instructions when giving this medicine to a youngster of any age. Do not use prescription drugs if you've got severe asthma, emphysema, or any other breathing problem, or should you are allergic to promethazine or another phenothiazines for example chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you have certain conditions, you may need a dose adjustment or special tests to securely use prescription drugs. Before you take promethazine, tell your doctor if you have:

a good reputation for seizures;

heart disease or high blood pressure;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or another breathing problem;

sleep apnea (breathing stops while sleeping);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or issues with urination;

low levels of calcium with your blood (hypocalcemia); or

if you've got ever were built with a serious complication when using promethazine or another phenothiazine.

FDA pregnancy category C. It isn't known whether promethazine is harmful to a baby. Tell your doctor in the event you are pregnant or prefer to conceive during treatment. It is not known whether promethazine passes into breast milk or if it might harm a nursing baby. Do not use this medication without telling your medical professional if you are breast-feeding a child. Older adults might be prone to have unwanted side effects from promethazine.

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