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Lioresal (Baclofen) is often a muscle relaxer plus an antispastic agent.

Baclofen is employed to treat muscle symptoms brought on by multiple sclerosis, including spasm, pain, and stiffness.

Baclofen could also be used for purposes unlisted in this medication guide.


Take just as prescribed because of your doctor. Do not take in larger or smaller amounts or longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally make positive changes to dose to successfully obtain the best results.
Call your doctor if the muscle symptoms tend not to improve after 14 days of taking this medication. Do not stop investing in this medication without first actually talking to a medical expert. You may have withdrawal symptoms like seizures or hallucinations, once you stop using baclofen after making use of it over a long period of time. You may need to use less prior to deciding to stop the medication completely.


Take the medicine as directed through your doctor.

Adult Patients with Spasticity of Spinal Cord Origin: After the first one day, for adult patients, the daily dosage ought to be increased slowly by 10- 30% increments and only once every a day, until the desired clinical effect is achieved.

Adult Patients with Spasticity of Cerebral Origin: After the first 24 hours, the daily dose must be increased slowly by 5- 15% only one time every 24 hours, prior to the desired clinical effect is achieved.

Pediatric Patients: After the first twenty four hours, the daily dose needs to be increased slowly by 5-15% just once every a day, until the desired clinical effect is achieved. If there is not just a substantive clinical reaction to increases inside the daily dose, check for proper pump function and catheter patency. Patients have to be monitored closely in the fully equipped and staffed environment in the screening phase and dose- titration period rigtht after implant. Resuscitative equipment needs to be immediately available for used in case of life- threatening or intolerable side effects.


Does not require refrigeration.

Do not store above 86°F (30°C).

Do not freeze.

Do not heat sterilize.


Active ingredient: Baclofen

Lioresal is often a muscle relaxant. It reduces how often and severity of muscle spasms that occur due to neurological disorders including multiple sclerosis.

Side Effects

Get emergency medical help for those who have these warning signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your physician at the same time for those who have a serious complication including:

seizure (convulsions);

confusion, hallucinations; or

an uneven heartbeat.

Less serious unwanted effects can include:

drowsiness, dizziness, weakness, tired feeling;


sleep problems (insomnia);

nausea, constipation; or

urinating more frequently than usual.

This is not a complete report on unwanted side effects yet others may occur.

Call your medical professional for medical health advice about unwanted effects.


You should not use baclofen should you be allergic for it.

To be sure you can safely take baclofen, tell your medical professional for those who have any of these other difficulties:

kidney disease;

epilepsy or another seizure disorder; or

a good reputation for stroke or blood clots.

Using baclofen may enhance your risk of developing a cyst on ovary. Talk with your doctor about your specific risk. FDA pregnancy category C. It is not known whether baclofen will harm an unborn baby. Tell your physician in case you are pregnant or intend to become pregnant when using medicines. It is not known whether baclofen passes into breast milk or if it may harm a nursing baby. You should not breast-feed while you are using baclofen. Do not give this medication to a child younger than 12 years. Older adults might be more sensitive to the results on this medicine.

Important safety information

This medication may impair your opinions or reactions. Be careful in case you drive or do just about anything that requires you to be alert. Drinking alcohol can increase certain unwanted effects of baclofen. Do not use baclofen during a period when muscle is required to assure safe balance and movement for sure activities. In some situations, it might endanger your physical safety to be in the state of reduced tone of muscle.


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