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Uses

INDICATIONS

Keppra is utilized to treat partial onset seizures in adults and children that are at the very least 1 month old.
It is additionally used to deal with tonic-clonic seizures in adults and youngsters that are at the very least 6 yrs . old, and myoclonic seizures in older adults and kids who're at least 12 years of age.

INSTRUCTIONS

Take Keppra exactly as prescribed because of your doctor. Do not take in larger or smaller amounts or over recommended. Follow the directions in your prescription label.

Your doctor may occasionally alter your dose to ensure that you acquire the best results.

Keppra is usually taken twice every day. Take the medicine simultaneously each day. You may take Keppra with or without food.

Measure liquid medicine which has a special dose-measuring spoon or medicine cup, not which has a regular table spoon. If you do not have a very dose-measuring device, ask your friendly phamacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be removed previously.

Use Keppra regularly to find the most benefit. Get your prescription refilled prior to deciding to run out of medication completely.

Do not stop using Keppra without first speaking with your physician, even if you feel fine. You might have increased seizures if you stop applying this medicine suddenly. You ought to use much less when you stop the medication completely.

Seizures in many cases are treated having a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions supplied with each medication. Do not alter your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card praoclaiming that you adopt Keppra. Any medical care provider who treats you need to understand that you adopt seizure medication.

To be sure Keppra is just not causing harmful effects, your kidney function ought to be tested. Visit your doctor regularly.

If you missed a dose - go ahead and take missed dose whenever you remember. Skip the missed dose if it's almost time for your next scheduled dose. Do not take extra medicine to produce inside the missed dose.

DOSAGE

Important Administration Instructions

Keppra emerged orally with or without food. The Keppra dosing regimen is determined by the indication, generation, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with bodyweight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with body weight above 20 kg.

When while using the oral solution in pediatric patients, dosing is weight-based (mg per kg) employing a calibrated measuring device (not just a household teaspoon or tablespoon).
Keppra tablets must be swallowed whole. Keppra tablets shouldn't be chewed or crushed.

Pediatric Patients

Treatment needs to be initiated using a daily dose of 14 mg/kg in 2 divided doses (7 mg/kg two times a day). The daily dose ought to be increased every 2 weeks by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg two times a day). In the clinical trial, the mean daily dose was 35 mg/kg in this age bracket. The effectiveness of lower doses is not studied.

Treatment needs to be initiated which has a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two times a day). The daily dose should be increased by 50 percent weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg two times a day). If a patient cannot tolerate a regular dose of 50 mg/kg, the daily dose could possibly be reduced. In the clinical study, the mean daily dose was 47 mg/kg with this generation.

Treatment needs to be initiated using a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice a day). The daily dose should be increased every 2 weeks by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). If a patient cannot tolerate an everyday dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment ought to be initiated which has a daily dose of 500 mg given as twice a day dosing (250 mg twice a day). The daily dose should be increased every 14 days by increments of 500 mg to a maximum recommended daily dose of 1500 mg (750 mg twice a day).

For Keppra tablet dosing in pediatric patients weighing greater than 40 kg, treatment needs to be initiated having a daily dose of 1000 mg/day given as twice daily dosing (500 mg twice a day). The daily dose should be increased every two weeks by increments of 1000 mg/day to your maximum recommended daily dose of 3000 mg (1500 mg two times a day).


Partial Onset Seizures
Adults 16 Years And Older

In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were been shown to be effective. Although in most studies there was clearly a propensity toward greater response with higher dose [see Clinical Studies], a regular surge in response to comprehend dose hasn't been shown.

Treatment ought to be initiated using a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments could possibly be given (1000 mg/day additional every 2 weeks) to some maximum recommended daily dose of 3000 mg. Doses in excess of 3000 mg/day are already employed in open-label studies for periods of half a year and longer. There is no evidence that doses higher than 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment needs to be initiated which has a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage ought to be increased by 1000 mg/day every 2 weeks towards the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day has not been studied.


Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment ought to be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage must be increased by 1000 mg/day every 14 days for the recommended daily dose of 3000 mg. The effectiveness of doses below 3000 mg/day is not adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment needs to be initiated using a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two times a day). The daily dose needs to be increased every two weeks by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). The effectiveness of doses less than 60 mg/kg/day hasn't been adequately studied. Patients with weight ≤ 20 kg needs to be dosed with oral solution. Patients with body weight above 20 kg can be dosed with either tablets or oral solution. Only whole tablets must be administered.


Adult Patients With Impaired Renal Function
Keppra dosing must be individualized according to the patient's renal function status.

STORAGE

Store Keppra at room temperature from moisture, heat, and lightweight.

Side Effects

Get emergency medical help in case you have all of these indications of a hypersensitivity to Keppra: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, including: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your medical professional at the same time in case you have a very serious side-effect for example:

Less serious Keppra negative effects can sometimes include:

This just isn't a complete list of side effects and others may occur. Tell a medical expert about any unusual or bothersome unwanted effect.

Precautions

You should not use Keppra if you are allergic to levetiracetam.

To be sure to can safely take Keppra, tell your medical professional if you have kidney disease or high blood pressure.

You might have thoughts about suicide while taking this medicine. Tell your doctor in case you have signs and symptoms of depression or suicidal thoughts throughout the first many weeks of treatment, or when your dose is changed.

Your family or any other caregivers should also be alert to changes in your mood or symptoms. Your doctor will likely need to check you at regular visits.

FDA pregnancy category C. It is not known whether Keppra will harm an baby, but developing a seizure while pregnant could harm both mother and also the baby. Tell a medical expert in the event you are pregnant or plan to conceive while applying this medication. Do not start or stop taking Keppra while pregnant without your physician's advice. Seizure control is essential while pregnant. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow your medical professional's instructions about taking Keppra while you are pregnant. Levetiracetam can pass into breast milk and may even harm a nursing baby. You should not breast-feed when you are using Keppra. Do not give this medication with a child devoid of the advice of an doctor. Your child's dose needs depend on age and weight. The child should remain under the care of your doctor while by using this medicine.

Do not stop using Keppra without first speaking with your medical professional, although you may feel great. You may have increased seizures if you stop using Keppra suddenly. You ought to use less and less before you stop the medication completely.

You could have thoughts about suicide while taking Keppra. Your doctor should check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your medical professional, including: mood or behavior changes, depression, anxiety, or should you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card on the grounds that you adopt Keppra. Any medical treatment provider who treats you have to know that you're taking seizure medication.

Keppra may impair your opinions or reactions. Be careful if you drive or do just about anything that requires you to be alert. Tell your medical professional in the event you are pregnant or prefer to conceive while employing this medication. Do not start or stop taking Keppra when pregnant without your medical professional's advice. Having a seizure while pregnant could harm the mother and also the baby. Seizure control is very important in pregnancy along with the benefits of preventing seizures may outweigh any risks resulting from using Keppra.

Avoid drinking alcohol. It can increase a number of the side effects of Keppra and may even also increase the potential risk of seizures. This medication may impair your thinking or reactions. Be careful in the event you drive or do just about anything that will need that you be alert.


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