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Endep can be a tricyclic antidepressant utilized to treat depression and chronic pain. Endep improves the the signs of depression by correcting the balance in the chemicals with your brain including norephinephrine and serotonin. These chemicals improve the climate in the patient and deal with depression.


Use Endep as directed from your doctor.


The dosage for Endep is determined by the condition in the patient. Only the doctors consider the amount the dosage ought to be given to someone. Usually a low dose of Endep is given in a certain period and will gradually increase depending on the tolerance and improvement of the patient.
Initial dosage usually starts at 75 milligrams up to 159 milligrams per day that is divided in smaller doses. For confined patients in hospitals, doctors usually administer 100 to 200 milligrams per day.
Elderly patients are generally supplied with low dosage because they are not capable of the tolerance due to their age. Doctors usually reduce the dosage as the patient improves. Constant monitoring with the patient’s condition is necessary in an attempt to see whether the dosage ought to be increased or decreased.

Ask your health care provider any queries you could have about how to make use of Endep.


Endep needs to be stored at room temperature from moisture and sunlight. Avoid storage at temperatures above 30°C (86°F). Keep Endep out with the reach of children.


Active ingredient: Amitriptyline.

Amitriptyline was approved by the FDA in May 1983.

Side Effects

All medicines could cause side effects, but some people have no, or minor, unwanted effects.

Check with your doctor if some of these most common negative effects persist or become bothersome:

Blurred vision; alternation in sexual desire or ability; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss in appetite; nausea; tiredness; sleep disorders; weakness.

Seek medical help without delay if any of these severe unwanted side effects occur:

Severe allergies (rash; hives; itching; lack of breath; tightness inside chest; swelling from the mouth, face, lips, or tongue); chest pain; confusion; dark urine; delusions; difficulty speaking or swallowing; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; new or worsening agitation, anxiety, panic and anxiety attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated sense of well-being, restlessness, or inability to sit still; numbness or tingling in the arm or; one-sided weakness; seizures; severe or persistent dizziness or headache; severe or persistent sleep disorders; slurred speech; suicidal thoughts or actions; tremor; trouble urinating; uncontrolled muscle movements (eg, of face, tongue, arms, legs); unusual bleeding or bruising; unusual or severe mental or mood changes; vision problems; yellowing from the skin or eyes.

This is not a complete set of all negative effects that may occur. If you've got queries about negative effects, contact your doctor.


Do NOT use Endep if:

Contact your physician or doctor straight away if any of these affect you.

Some health conditions may talk with Endep. Tell a medical expert or pharmacist in case you have any medical conditions, in particular when any with the following connect with you:

Some medicines may talk with Endep. Tell your health care provider if you take any other medicines, especially any from the following:

This may not be a complete set of all interactions that may occur. Ask your health care provider if Endep may talk with other medicines which you take. Check together with your physician when you start, stop, or alter the dose from a medicine.

Important safety information:

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