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Eldepryl is indicated as a possible adjunct inside treating Parkinsonian patients being treated with levodopa/carbidopa who exhibit deterioration in the quality with their reaction to this therapy.


Take this medicine only as directed because of your doctor. Do not take a greater portion of it, don't take it more often, and don't take on it for a longer time than your doctor ordered.

It is best to adopt this medicine before breakfast and without liquids.

If you happen to be while using the disintegrating tablet, ensure the hands are dry before you handle the tablet. Do not open the blister pack that contains these days until you are ready to go on it. Remove today from your blister pack by peeling back the foil, then taking today out. Do not push the tablet with the foil. Do not break or split these days. Place these days for the top of your tongue, where it's going to melt quickly. Do not eat food or drink liquids for 5 minutes before or after investing in this medicine.

If you miss a dose of this medicine, take it as quickly as possible. However, when it is almost time for your next dose, skip the missed dose and get back to your normal dosing schedule. Do not double doses.


The dose with this medicine changes for different patients. Follow your physician's orders or directions on the label. The following information includes merely the average doses on this medicine. If your dose differs, tend not to put it back unless your physician informs you for this.

The amount of medicine that you take depends around the strength from the medicine. Also, the volume of doses you adopt daily, the time allowed between doses, and also the time period you are taking the medicine depend about the condition for which you're while using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in a very closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out of your reach of youngsters.
Do not keep outdated medicine or medicine no more needed.


Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly referred to in the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along with its needed effects, a medicine may cause some unwanted side effects. Although not all of these unwanted effects may occur, if they occur they may need medical attention.

Check with your doctor immediately if any of the following unwanted side effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements of the body
increased sensitivity of the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood and other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if getting up coming from a lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling stuff that aren't there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside hands, feet, or lips
puffing of the cheeks
rapid or worm-like movements with the tongue
restlessness or want to keep moving
severe stomach pain
shakiness inside legs, arms, hands, or feet
shortness of breath
swelling from the feet or lower legs
swelling or inflammation of the mouth
tightness within the chest
trembling or shaking with the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements with the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds

Get emergency help immediately if the following signs of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure level
severe spasm the location where the head and heels are bent backward and also the body arched forward
troubled breathing

Some unwanted side effects may occur that usually tend not to need medical attention. These unwanted side effects may go away during treatment since your body adjusts for the medicine. Also, your overall health care professional may be able to tell you about ways to prevent or reduce some of these unwanted side effects. Check using your health care professional if any of these negative effects continue or are bothersome or if you've questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning in the lips, mouth, or throat
dryness or soreness with the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing inside the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing with the eyelids
unusual sense of well-being
unusual weight loss
voice changes

Other unwanted effects unlisted could also appear in some patients. If you notice some other effects, check using your doctor.


It is essential that your doctor look at the progress at regular visits to allow for adjustments to your dose and to look for any negative effects.

Do not take selegiline if you might have used meperidine (e.g., Demerol®) or an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past two weeks. If you do, you could possibly develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you're by using this medicine. Using these medicines together might cause uncomfortable side effects.

Selegiline might cause serious unwanted side effects when used along with some antidepressants. Tell your physician if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less per day for that management of Parkinson's disease, there aren't any restrictions on food or beverages you consume or drink. However, the possibility exists that dangerous reactions, such as sudden high blood pressure, may occur if doses higher than those useful for Parkinson's disease are taken with food items, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for about 2 weeks as soon as you stop investing in this medicine, simply because, beverages, and also other medicines may continue to react with selegiline if it was used doses greater than those usually used by Parkinson's disease.

Check with a medical expert or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you're using this medicine. These may be symptoms of a serious side effect that should have a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you get up coming from a lying or sitting position. Getting up slowly can help. If the problem continues or gets worse, check with your doctor.

Selegiline might cause dryness in the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice with your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check along with your medical professional or dentist. Continuing dryness in the mouth may increase the opportunity of dental disease, including tooth decay, gum disease, and fungus infections.

It is important that your physician look at skin for melanoma (tumor) regularly if you might have Parkinson's disease.

Do not stop using this medicine without first checking with a medical expert. Your doctor may wish one to reduce gradually the amount you are taking before stopping completely.

Hallucinations may appear in some patients. This is more common with elderly patients. If you have hallucinations, talk with your medical professional.

Some individuals who have used this medicine had unusual adjustments to their behavior. Talk with your doctor should you start experiencing difficulity with gambling or increased sexual libido while using this medicine.

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