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Depakote can be used to treat various types of seizure disorders. It is sometimes used in addition to other seizure medications. It is also used to take care of the manic phase of bipolar disorders (manic-depressive illness), and prevent headaches. Depakote affects chemicals by the body processes which may be associated with causing seizures.


Use Depakote as directed from your doctor.

Ask your health care provider questions maybe you have regarding how to make use of Depakote.


Store Depakote between 68 and 77 degrees F (20 and 25 degrees C). Store faraway from heat, moisture, and light-weight. Do not store within the bathroom. Keep Depakote out from the reach of children and far from pets.


Active Ingredient: Divalproex.

Side Effects

All medicines might cause negative effects, but a majority of everyone has no, or minor, unwanted side effects.

Check with your physician if some of these most common unwanted effects persist or become bothersome:

Change in appetite; constipation; diarrhea; dizziness; drowsiness; baldness; headache; indigestion; nausea; stomach cramps or pain; trouble sleeping; vomiting; weakness; weight changes.

Seek medical help without delay if these severe unwanted effects occur:

Severe allergy symptoms (rash; hives; itching; lack of breath; tightness in the chest; swelling in the mouth, face, lips, or tongue); abnormal thinking; alternation in monthly period; adjustments to behavior; chest pain; confusion; dark, tarry, or bloody stools; dark urine; difficulty speaking; difficulty urinating or other urination problems; extreme tiredness; fast or irregular heartbeat; hallucinations; hearing loss; involuntary movements with the legs and arms; involuntary movements or chewing movements in the face, jaw, mouth, or tongue; joint; deficiency of energy; lack of appetite; loss in coordination; lack of seizure control; loss of memory; new or worsening mental or mood changes (eg, aggressiveness, agitation, anxiety, depression, exaggerated feeling of well-being, hostility, impulsiveness, inability to sit still, irritability, panic disorder, restlessness); nosebleed; pounding in the chest; red, swollen, blistered, or peeling skin; severe or persistent nausea, vomiting, or stomach pain; lack of breath; suicidal thoughts or actions; swelling from the arms or legs; signs of infection (eg, fever, chills, sore throat); tremor; unusual bleeding or bruising; unusual weakness; vision changes or blurred vision; yellowing in the skin or eyes.

 This is not a whole report on all negative effects that could occur. If you might have questions on unwanted side effects, contact your medical provider.


Do NOT use Depakote if:

Contact your medical professional or physician without delay if all of these apply to you.

Some health concerns may interact with Depakote. Tell your medical professional or pharmacist when you have any health concerns, especially if any of the following affect you:

Some medicines may interact with Depakote. Tell your health care provider in case you are taking any other medicines, especially any from the following:

This may not be a whole listing of all interactions which could occur. Ask your doctor if Depakote may talk with other medicines that you adopt. Check with your medical provider before you begin, stop, or affect the dose of the medicine.

Important safety information:

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