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INDICATIONS

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Chloroquine is indicated for your suppressive treatment as well as acute attacks of malaria as a result of P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum. The drug is also indicated for your treatments for extraintestinal amebiasis.

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Take chloroquine with meals or milk to reduce stomach upset, unless otherwise directed by your doctor.

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t is critical that you simply take chloroquine only as directed. Do not take a greater portion of it, don't take it more regularly, and don't take on it for a longer time than a medical expert ordered. To do so may increase the possibility of serious side effects.

If you take chloroquine to keep you against getting malaria, keep taking it for the full time of treatment. If you already have malaria, you should still keep taking chloroquine for that fulltime of treatment even if you start to feel better after a couple of days. This will help to clear your infection completely. If you stop taking chloroquine too soon, your symptoms may return.

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Chloroquine is best suited once you take it on a regular schedule. For example, if you're to go once per week to stop malaria, it is best to get it on the same day every week. Or if you're to take two doses every day, one dose could be taken with breakfast along with the other while using evening meal. Make sure which you don't miss any doses. If you have any questions concerning this, talk with your wellbeing care professional.

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If you miss a dose of chloroquine, go at the earliest opportunity. However, if it's almost time for your upcoming dose, skip the missed dose and get back to your regular dosing schedule. Do not double doses.

DOSAGE 

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The dosage of chloroquine phosphate is usually expressed in terms of equivalent chloroquine base. Each 500 mg tablet of ARALEN has the same in principle as 300 mg chloroquine base. In infants and children the dosage is preferably calculated by bodyweight.

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Malaria: Suppression - Adult Dose: 500 mg (= 300 mg base) on exactly the same day of every week.

Pediatric Dose: The weekly suppressive dosage is 5 mg calculated as base, per kg of bodyweight, but must not exceed the adult dose irrespective of weight.

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If circumstances permit, suppressive therapy has to start a fortnight prior to exposure. However, failing this in grown-ups, a primary double (loading) dose of merely one g (= 600 mg base), or perhaps in children 10 mg base/kg could possibly be drawn in two divided doses, six hours apart. The suppressive therapy ought to be continued for eight weeks after leaving the endemic area.
For Treatment of Acute Attack.

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Adults: An initial dose of a single g (= 600 mg base) accompanied by one more 500 mg (= 300 mg base) after six to eight hours and a single dose of 500 mg (= 300 mg base) on every one of two consecutive days. This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in 3 days.

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The dosage for adults of low weight as well as infants and children should be determined as follows:

First dose: 10 mg base per kg (however, not exceeding one particular dose of 600 mg base).

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Second dose: (6 hours after first dose) 5 mg base per kg (however, not exceeding just one dose of 300 mg base).

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Third dose: (24 hours after first dose) 5 mg base per kg.

Fourth dose: (36 hours after first dose) 5 mg base per kg.

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For radical cure of vivax and malariae malaria concomitant therapy having an 8-aminoquinoline compound is essential.

Extraintestinal Amebiasis: Adults,1 g (600 mg base) daily for 2 days, then 500 mg (300 mg base) daily for around 2-3 weeks. Treatment is usually combined with an effective intestinal amebicide.

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Store the medicine in a very closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.

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Keep from the reach of kids.

Do not keep outdated medicine or medicine no longer needed.

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Side Effects

Along having its needed effects, medication may cause some unwanted side effects. Although not many of these negative effects may occur, if they happen they could need medical assistance. When chloroquine is utilized in short periods of time, unwanted effects are often rare. However, when it is employed for a very long time and/or perhaps in high doses, unwanted side effects may occur and may be serious.

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Check with your physician immediately if any of the following side effects occur:
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Note: The unwanted effects inside the Less Common category above can also occur or deteriorate once you stop taking chloroquine.

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Some unwanted side effects may occur that usually tend not to need medical assistance. These unwanted effects may go away during treatment since your body adjusts for the medicine. Also, your wellbeing care professional could be able to share with you ways to stop or reduce some side effects. Check with your health care professional if these things side effects continue or are bothersome or if you've questions about them:

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Other side effects unlisted may also happen in some patients. If you notice every other effects, talk with your health care professional.

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Precautions

If you'll be taking chloroquine for quite a while, it is vital that a medical expert check you at regular visits for any blood problems or muscle weakness that might be due to chloroquine. In addition, consult your physician immediately if blurred vision, difficulty in reading, or another alternation in vision occurs during or after treatment. Your doctor might want that you have the eyes checked by an ophthalmologist (eye doctor).

If your symptoms tend not to improve within a couple of days or when they become worse, consult your medical professional.

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Make sure you are aware how you reply to chloroquine before you decide to drive, use machines, or a single thing else that may be dangerous if you're not able to see well.

Chloroquine could potentially cause blurred vision, difficulty in reading, and other alternation in vision. It could also cause some individuals to get lightheaded.

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If these reactions are specially bothersome, talk with your doctor.

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Certain medicines must not be used at or around the time of consuming food or eating some kinds of food since interactions may occur. Using alcohol or tobacco with certain medicines can also cause interactions that occurs. Discuss along with your healthcare professional the usage of your medicine with food, alcohol, or tobacco.

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There aren't any adequate and well-controlled studies evaluating the security and efficacy of chloroquine in expectant women. Usage of chloroquine while pregnant ought to be avoided except within the suppression or treatment of malaria when inside the judgment from the physician the main benefit outweighs the potential risk towards the fetus.

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